메틸(1-트리메틸실릴)아크릴레이트 C화학적 특성, 용도, 생산
물리적 성질
bp 75 °C/50 mmHg, 152 °C/690 mmHg.
용도
Methyl 2-Trimethylsilylacrylate is widely used as reactive, α-silyl Michael acceptor for conjugate addition of carbanions,
enolate anions, organolithium reagents, and Grignard
reagents; affords 3-cyclopentenecarboxylates and cyclohexanecarboxylates
by [3 + 2] and [4 + 2] annulation methods; provides
α-silyl esters and vinylsilanes by organolithium conjugate
additions.
제조 방법
Methyl 2-Trimethylsilylacrylate is prepared by the reaction of (E)-2-
(trimethylsilyl)vinyllithium with methyl chloroformate or by
carbonation of the corresponding Grignard reagent prepared
from (1-bromovinyl)trimethylsilane, giving 2-trimethylsilylacrylic
acid. The methyl ester is prepared from the acid
by direct esterification with absolute methanol in the presence
of mineral acid, by reaction with diazomethane at low temperature,
or by treatment with BF3·MeOH complex.
메틸(1-트리메틸실릴)아크릴레이트 준비 용품 및 원자재
원자재
준비 용품
