가도베르세타미드(200MG)

가도베르세타미드(200MG)
가도베르세타미드(200MG) 구조식 이미지
카스 번호:
131069-91-5
한글명:
가도베르세타미드(200MG)
동의어(한글):
가도베르세타미드(200MG)
상품명:
GADOVERSETAMIDE (200 MG)
동의어(영문):
GADOVERSETAMIDE (200 MG);Gadoversetamide (200 mg) (DISCONTINUED)
CBNumber:
CB1500507
분자식:
C20H34GdN5O10
포뮬러 무게:
661.77
MOL 파일:
131069-91-5.mol

가도베르세타미드(200MG) 속성

밀도
d25 1.160

안전

HS 번호 2846909000
유해 물질 데이터 131069-91-5(Hazardous Substances Data)
독성 LD50 i.v. in mice: 30.3 mmol/kg (Periasamy)

가도베르세타미드(200MG) C화학적 특성, 용도, 생산

개요

The contrast agent gadoversetamide was launched in the US as a solution for i.v. injection to be used prior to magnetic resonance imaging (MRI) in patients with anomalous blood-brain barrier or anomalous vascularity in the central nervous system or in the liver. This chelate obtained by complexation of paramagnetic gadolinium(III) ion and DTPA-bis- (methoxyethylamide) ligand enhances visualization of lesions including tumors in the brain, spine and liver due to the effect of Gd(III)-water interaction on the proton magnetic relaxation of water. The small molecular size gadoversetamide belongs to the class of extracellular contrast agents. A phase III, multicenter, double-blind, parallel group trial showed that gadoversetamide was well tolerated and as efficient as gadopentetate dimeglumine (Schering) in hepatic magnetic resonance imaging of patients with suspected liver pathology.

용도

Diagnostic aid (paramagnetic, brain disorders; spine disorders.

정의

ChEBI: A gadolinium coordination entity that consists of Gd3+ coordinated to 3,6,9-triazaundecadiamide in which each of the amide nitrogens is substituted by a 2-methoxyethyl group and in which the nitrogens at positions 3, 6, and 9 are each ubstituted by carboxylatomethyl group. The gadolinium is coordinated to the three tertiary amino groups as well as to the carboxylate groups. A white odourless powder that is freely soluble in water, gadoversetamide has paramagnetic properties and is used s a contrast agent in magnetic resonance imaging. It distributes mainly in extracellular fluid, but does not cross the blood-brain barrier. It is used particularly in imaging the brain, spine and liver.

가도베르세타미드(200MG) 준비 용품 및 원자재

원자재

준비 용품


가도베르세타미드(200MG) 공급 업체

글로벌( 21)공급 업체
공급자 전화 이메일 국가 제품 수 이점
AFINE CHEMICALS LIMITED
+86-0571-85134551
info@afinechem.com China 15395 58
Wuhan Topule Biopharmaceutical Co., Ltd
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masar@topule.com China 8474 58
Aladdin Scientific
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sales@aladdinsci.com United States 57511 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2127 70
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
sj_scrc@sinopharm.com China 9823 79
Shanghai Changyan Chem & Tech Co., Ltd. 021-021-20242659 18930833303
order@changyanchem.com China 5008 55
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
2853530910@QQ.com China 8012 62
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684
sales@rrkchem.com China 56057 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44941 58

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