DOFETILIDE-D4
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DOFETILIDE-D4 속성
- 녹는점
- 130-1350C
- 저장 조건
- -20°C Freezer
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 하얀색
- CAS 데이터베이스
- 1189700-56-8
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
DOFETILIDE-D4 C화학적 특성, 용도, 생산
개요
Dofetilide-d4 is intended for use as an internal standard for the quantification of dofetilide by GC- or LC-MS. Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes). However, at 1 μM, dofetilide has pro-arrhythmic activity, inducing early afterdepolarizations (prolonged repolarization) in cell models and Torsade de Pointes in a rabbit screen for proarrhythmic properties when administered at a dose of 10 mg/kg. Formulations containing dofetilide have been used in the treatment of highly symptomatic atrial fibrillation and the conversion of flutter to normal sinus rhythm.화학적 성질
White Crystalline Solid용도
Dofetilide-d4 is intended for use as an internal standard for the quantification of Dofitilide by GC- or LC-mass spectrometry.DOFETILIDE-D4 준비 용품 및 원자재
원자재
준비 용품
DOFETILIDE-D4 공급 업체
글로벌( 34)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32344 | 50 |
Artis Biotech Co. Ltd. | 19138486554 18582380095 |
sales@artisbio.com | China | 2754 | 58 |
Clearsynth Canada Inc. | +1.415.685.4395 |
enquiry@clearsynth.com | Canada | 912 | 58 |
Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 |
wxf@sungening.com | China | 9592 | 60 |
Chengdu Novel Biomedical Co., Ltd. | 028-85255396 18302801538 |
cdnovell@163.com | China | 2276 | 58 |
Shanghai ring qi biological technology co., LTD | 13524106587 |
sales@hq-chem.com | China | 225 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 |
sales@rrkchem.com | China | 56057 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
Wuxi Minglu Medicine technology Co.,Ltd. | 0510-88726693 |
3204601684@qq.com | China | 2216 | 58 |