L-Ser-OBzl.HCl

L-Ser-OBzl.HCl 구조식 이미지
카스 번호:
60022-62-0
상품명:
L-Ser-OBzl.HCl
동의어(영문):
H-SER-OBZL·HCL;H-SER-OBZL HCL;SERINE-OBZL HCL;H-L-Ser-OBzl.HCl;L-SerinebenzylesterHCl;H-L-Ser-Obzl*Hydrochloride;L-SERINE BENZYL ESTER HYDROCHLORIDE;L-SerineBenzylEsterHydrochloride>Benzyl serinate hydrochloride (1:1);benzyl (2S)-2-amino-3-hydroxypropanoate
CBNumber:
CB2286886
분자식:
C10H14ClNO3
포뮬러 무게:
231.68
MOL 파일:
60022-62-0.mol
MSDS 파일:
SDS

L-Ser-OBzl.HCl 속성

녹는점
175°C
굴절률
-12 ° (C=1, H2O)
저장 조건
Inert atmosphere,Store in freezer, under -20°C
물리적 상태
powder to crystal
색상
흰색에서 거의 흰색
수용성
물에 용해됩니다.
InChI
InChI=1/C10H13NO3.ClH/c11-9(6-12)10(13)14-7-8-4-2-1-3-5-8;/h1-5,9,12H,6-7,11H2;1H/t9-;/s3
InChIKey
MGZWCDQAKCHOBX-FVGYRXGTSA-N
SMILES
C(OCC1=CC=CC=C1)(=O)[C@H](CO)N.[H]Cl |&1:10,r|
CAS 데이터베이스
60022-62-0(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
안전지침서 24/25
WGK 독일 3
HS 번호 29225090
그림문자(GHS):
신호 어:
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
1
0 0

L-Ser-OBzl.HCl C화학적 특성, 용도, 생산

개요

L-Serine benzyl ester hydrochloride, also known as L-Serine-Bz-HCl, is a derivative of the amino acid L-Serine. It is a water-soluble, white crystalline powder and is commonly used as a reagent in biochemical and physiological studies. It is a useful raw material that could synthesize mang organic compounds, such as a cyclic sulfamidate which could reacted cleanly with the sodium thiolate salt of a variety of unprotected 1-thio sugars in aqueous buffer to afford the corresponding S-linked amino acid glycoconjugates in good yields after hydrolysis of the N-sulfates[1].
L-Serine benzyl ester hydrochloride

화학적 성질

Colorless solid

용도

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

제조 방법

Boc-L-Ser-OBz (2.953 g, 10 mmol) was dissolved in MeOH (21 mL) and was palced in ice bath. Then concentrated hydrochloric acid (4.25 mL) was added dropwise. The ice bath was removed and the reaction mixture was stirred for 3 hours. After that the isopropanol (10 mL) was added and the volatile components were removed under reduced pressure at 55 ℃. The oily residue was coevaporated with isopropanol three times (3x10 mL). L-Serine benzyl ester hydrochloride ( yield=69%) was crystallized from H2O/iPr-OH/acetone mixture.
L-Serine benzyl ester hydrochloride

L-Ser-OBzl.HCl 준비 용품 및 원자재

원자재

준비 용품


L-Ser-OBzl.HCl 공급 업체

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