KPT-8602

KPT-8602 구조식 이미지
카스 번호:
1642300-52-4
상품명:
KPT-8602
동의어(영문):
CS-2388;ATG-016;ONO-7706;KPT-8602;Eltanexor;KPT-8602 (KPT 8602;Eltanexor (KPT-8602;(E)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-(pyrimidin-5-yl)acrylamide;5-Pyrimidineacetamide, α-[[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]methylene]-, (αE)-
CBNumber:
CB23151727
분자식:
C17H10F6N6O
포뮬러 무게:
428.3
MOL 파일:
1642300-52-4.mol

KPT-8602 속성

끓는 점
574.4±60.0 °C(Predicted)
밀도
1.57±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO에 용해됨
물리적 상태
Solid
산도 계수 (pKa)
13.06±0.50(Predicted)
색상
Off-white to light yellow

안전

KPT-8602 C화학적 특성, 용도, 생산

용도

(αE)?-α-?[[3-?[3,?5-?bis(Trifluoromethyl)?phenyl]?-?1H-?1,?2,?4-?triazol-?1-?yl]?methylene]?-?5-pyrimidineacetamide is an exportin-1 inhibitor with anti-leukemic activity. Exportin-1 mediates nuclear trafficking of proteins. (αE)?-α-?[[3-?[3,?5-?bis(Trifluoromethyl)?phenyl]?-?1H-?1,?2,?4-?triazol-?1-?yl]?methylene]?-?5-pyrimidineacetamide can be used to develop treatments for acute lymphoblastic leukemia.

KPT-8602 준비 용품 및 원자재

원자재

준비 용품


KPT-8602 공급 업체

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TargetMol Chemicals Inc.

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Amadis Chemical Company Limited
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