Metacycline hydrochloride
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Metacycline hydrochloride 속성
- 녹는점
- >224°C(dec.)
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- DMSO(약간 용해됨, 가열), 메탄올(약간 용해됨, 가열, 초음파 처리), 물(약간 용해됨)
- 물리적 상태
- 결정성 분말
- 색상
- 노란색
- BRN
- 5470951
- CAS 데이터베이스
- 3963-95-9
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 안전지침서 | 24/25-22 | ||
|---|---|---|---|
| WGK 독일 | 2 | ||
| RTECS 번호 | QI9276000 | ||
| HS 번호 | 29413020 | ||
| 독성 | LD50 in rats, mice (mg/kg): 252, 288 i.p. (Goldenthal) |
Metacycline hydrochloride C화학적 특성, 용도, 생산
개요
Methacycline is a tetracycline-class antibiotic that is active against a wide range of Gram-positive and Gram-negative organisms. It is readily absorbed from the gastrointestinal tract and reaches a maximum concentration at about the fourth hour, declining to a negligible amount in about 24 hours. It is more active than tetracycline against a number of bacteria.화학적 성질
yellow crystalline powder용도
Broad spectrum, semisynthetic antibiotic related to Tetracycline. Antibacterial.일반 설명
The synthesis of methacycline, 6-deoxy-6-demethyl-6-methylene-5-oxytetracycline hydrochloride (Rondomycin), reportedby Blackwood et al. in 1961, was accomplished bychemical modification of oxytetracycline. It has an antibioticspectrum like that of the other tetracyclines but greater potency;about 600 mg of methacycline is equivalent to 1 g oftetracycline. Its particular value lies in its longer serum halflife;doses of 300 mg produce continuous serum antibacterialactivity for 12 hours. Its toxic manifestations and contraindicationsare similar to those of the other tetracyclines.The greater stability of methacycline, both in vivo and invitro, results from modification at C-6. Removal of the 6-hydroxy group markedly increases the stability of ring C toboth acids and bases, preventing the formation of isotetracyclinesby bases. Anhydrotetracyclines still can form, however,by acid-catalyzed isomerization under strongly acidicconditions. Methacycline hydrochloride is a yellow to darkyellow, crystalline powder that is slightly soluble in waterand insoluble in nonpolar solvents. It should be stored intight, light-resistant containers in a cool place.
Metacycline hydrochloride 준비 용품 및 원자재
원자재
준비 용품
Metacycline hydrochloride 공급 업체
글로벌( 263)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21675 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29900 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 |
marketing1@neostarunited.com | China | 12330 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Hebei Miaobian Biotechnology Co., Ltd | +8617733850068 |
CHINA | 979 | 58 | |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 |
CHINA | 2783 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34571 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 9030 | 58 |
Metacycline hydrochloride 관련 검색:
5-플루오로-2'-디옥시유리딘 옥시테트라시클린
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METHACYCLINE HCL,METHACYCLINE HYDROCHLORIDE,Methacycline Hydrochloride BP73/USP25
1-ACETYL-1-CYCLOHEXENE