데소제스트렐
|
|
데소제스트렐 속성
- 녹는점
- 109-110°C
- 알파
- D20 +55° (chloroform)
- 끓는 점
- 390.62°C (rough estimate)
- 밀도
- 1.0169 (rough estimate)
- 굴절률
- 1.5100 (estimate)
- 저장 조건
- -20°C Freezer
- 용해도
- 물에는 거의 녹지 않으며, 메탄올에는 잘 녹고, 무수 에탄올과 염화메틸렌에는 잘 녹습니다.
- 물리적 상태
- Solid
- 산도 계수 (pKa)
- 13.07±0.40(Predicted)
- 색상
- 흰색에서 거의 흰색
- Merck
- 14,2926
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
안전지침서 | 24/25 | ||
---|---|---|---|
유엔번호(UN No.) | UN 3077 9 / PGIII | ||
WGK 독일 | 3 | ||
RTECS 번호 | JF7975000 | ||
HS 번호 | 29372390 | ||
유해 물질 데이터 | 54024-22-5(Hazardous Substances Data) |
그림문자(GHS): | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
신호 어: | Danger | ||||||||||||||
유해·위험 문구: |
|
||||||||||||||
예방조치문구: |
|
데소제스트렐 C화학적 특성, 용도, 생산
개요
Desogestrel is a synthetic progestogen. It inhibits ovulation and prevents fertilization in rabbits and mice. Desogestrel inhibits rhodamine 123 efflux, a measure of P-glycoprotein activity, ex vivo in human lymphocytes and CD8+ T cells in a dose-dependent manner. Formulations containing desogestrel have been used as oral contraceptives and for the treatment of polycystic ovary syndrome.화학적 성질
White Solid용도
A progestogen with low androgenic potency일반 설명
Desogestrel, (17α)-13-ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol, is a 19-nortestosterone analog with good progestin activity. Likethe other progestins, it is orally active and used in combinationwith an estrogen in oral contraceptives. Desogestrel is aprodrug that must be oxidized to the 3-one in vivo to haveprogestational action. CYPs 2C9 and 2C19 have been implicatedin the initial hydroxylation of desogestrel at C3.Clinical Use
Desogestrel also is a prodrug and is rapidly metabolized in the intestinal mucosa and on first pass through the liver to its active metabolite, etonogestrel (3-ketodesogestrel). Following oral administration, the relative bioavailability for desogestrel is approximately 84%. Desogestrel also exhibits high selectivity for the progesterone receptor and low and rogenic activity, and it does not diminish the beneficial effects of estrogen on the lipid profile.데소제스트렐 준비 용품 및 원자재
원자재
준비 용품
데소제스트렐 공급 업체
글로벌( 327)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 615 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21634 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29881 | 58 |
TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 |
sales@tianpharm.com | CHINA | 304 | 58 |
Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 |
sales@czwytech.com | CHINA | 904 | 58 |
Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 |
sales@amoychem.com | China | 6383 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 |
Hebei shuoxi biotechnology co. LTD | +8613081092107 |
CHINA | 964 | 58 | |
Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 +86-15850508050 |
sean.lv@synzest.com | China | 323 | 58 |
데소제스트렐 관련 검색:
에틸파라벤 에틸 5,5-디페닐-2-이소사졸린-3-카르복실레이트 에틸알코올 2-하이드록시에틸 메틸 에테르 셀룰로오즈 아크릴산에틸 4,4′-메틸렌 비스(페닐 이소시아네이트)(고체) 메틸렌블루 초산에틸 프레그네놀원 아세테이트 메틸에틸케톤
chlorempenthrin
Empenthrin
3-KETO DESOGESTREL
Lynestrenol
16,17-Epoxypregnenolone
Methylene Chloride
16,17-Epoxypregnenolone acetate
DESOGESTREL RELATED COMPOUND B (15 MG) (3-HYDROXY-DESOGESTREL)