메드리손

메드리손
메드리손 구조식 이미지
카스 번호:
2668-66-8
한글명:
메드리손
동의어(한글):
메드리손
상품명:
MEDRYSONE
동의어(영문):
u8471;MEDRYSONE;nsc-63278;Mderysone;hmsliquifilm;Medrysone (500 mg);inhibit,Medrysone,HMS,Inhibitor;6A-methyl-11B-hydroxyprogesterone;6α-methyl-11β-Hydroxyprogesterone;6ALPHA-METHYL-11BETA-HYDROXYPROGESTERONE
CBNumber:
CB2490249
분자식:
C22H32O3
포뮬러 무게:
344.5
MOL 파일:
2668-66-8.mol

메드리손 속성

녹는점
155-158°
알파
D +189° (in chloroform)
끓는 점
492.3±45.0 °C(Predicted)
밀도
1.13±0.1 g/cm3(Predicted)
저장 조건
2-8°C
용해도
아세톤(약간 용해됨), 클로로포름(약간 용해됨), 메탄올(약간 용해됨, 초음파 처리)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
14.53±0.70(Predicted)
색상
흰색에서 황백색까지

안전

WGK 독일 3
RTECS 번호 TU5250000

메드리손 C화학적 특성, 용도, 생산

개요

6α-methyl-11β-hydroxy Progesterone is an anti-inflammatory steroid. It is a hydroxylated progesterone that lacks progestational and androgenic activity. It inhibits phytohemagglutinin-activated T cell proliferation in vitro with an IC50 value of 2.9 μg/ml. 6α-methyl-11β-hydroxy Progesterone also inhibits TNF-α production in LPS-stimulated THP-1 cells (IC50 = 30.54 μg/ml). Topical formulations containing 6α-methyl-11β-hydroxyprogesterone have been used to treat inflammatory ocular diseases.

용도

Medrysone is a corticosteroid that is seen to increase intraocular pressure.

메드리손 준비 용품 및 원자재

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