세포라니드
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세포라니드 속성
- 녹는점
- >150° (dec)
- 밀도
- 1.79±0.1 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- 용해도
- 알칼리성 용액(약간), DMSO(약간, 가온), 메탄올(약간)에 용해됨
- 산도 계수 (pKa)
- 2.52±0.10(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 옅은 갈색까지
- 안정성
- 흡습성
- InChIKey
- SLAYUXIURFNXPG-CRAIPNDOSA-N
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| HS 번호 | 2941906000 | ||
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| 기존화학 물질 | KE-01465 |
| 그림문자(GHS): |
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| 신호 어: | Danger | |||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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세포라니드 C화학적 특성, 용도, 생산
개요
Ceforanide is a second generation cephalosporin with good β-lactamase resistance. It has a serum half-life of about three hours, allowing twice-daily dosing.용도
Ceforanide is a cephalosporin based antibiotic used in the sterilization in various medical procedures.정의
ChEBI: A second-generation cephalosporin antibiotic with {[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and 2-(aminomethyl)phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is effective against many col forms, including Escherichia coli, Klebsiella, Enterobacter and Proteus, and most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Ari ona species.Antimicrobial activity
A semisynthetic parenteral cephalosporin with activity broadly similar to that of cefalotin. Its activity in vitro is significantly reduced in the presence of serum. A 1 g intravenous dose achieves a concentration of c. 135 mg/L at the end of infusion. The response after 0.25, 0.5 and 1 g intravenous doses is essentially linear. A 1 g intramuscular dose produces mean peak values of around 70 mg/L. Plasma protein binding is around 85%.It is almost entirely eliminated in the urine with a halflife of about 2.5 h, 80–95% being recovered in the first 12 h. The half-life is inversely related to renal function, rising to around 20 h when the creatinine clearance falls below 5 mL/min. About half the dose is removed by hemodialysis over 6 h.
It is generally well tolerated; phlebitis and pain at the site of injection are reported in some patients with occasional transient neutropenia and increased transaminase levels. It has been used principally for the treatment of infections due to Gram-positive cocci, including staphylococcal and streptococcal soft-tissue infections, but is no longer widely available.
세포라니드 준비 용품 및 원자재
원자재
준비 용품
세포라니드 공급 업체
글로벌( 87)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34571 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 8840 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9641 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 |
2571773637@qq.com | China | 9827 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
세포라니드 관련 검색:
아세틸 염화물 아세트아미노펜 2,4-펜탄디온 아세틸 보조 효소 A 페닐초산
PHENYL VALERATE
2-(5-Mercaptotetrazole-1-yl)ethanol
1H-Tetrazole-1-acetic acid
7-TMCA
7-Phenyl-acetamido-deacetoxy-cephalosporanic-acid
1-Ethyl-1H-1,2,3,4-tetrazole-5-thiol
2-aminomethylphenylacetic acid (intermediate of ceforanide)
5-Mercapto-1H-tetrazole-1-acetic acid
1-ETHYL-1H-TETRAZOLE
Ceforanide
Acetyl-resveratrol
ACETAMINOPHENOL BP/USP
1H-Tetrazole, 5-((3-(ethylthio)propyl)thio)-1-methyl-