Ceforanide

Ceforanide Struktur
60925-61-3
CAS-Nr.
60925-61-3
Englisch Name:
Ceforanide
Synonyma:
C06884;BL-S-786;Ceforanide;CEFORANIDE (200 MG);Antibiotic BL-S-786;Ceforanide USP/EP/BP;Ceforanide (1097807);2-(2,4-Dimethylphenyl)sulf;Bacterial,inhibit,Antibiotic,Inhibitor,Ceforanide;(6R,7R)-7-(2-(2-(Aminomethyl)phenyl)acetamido)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CBNumber:
CB2501637
Summenformel:
C20H21N7O6S2
Molgewicht:
519.55
MOL-Datei:
60925-61-3.mol

Ceforanide Eigenschaften

Schmelzpunkt:
>150° (dec)
Dichte
1.79±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Löslichkeit
Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
pka
2.52±0.10(Predicted)
Aggregatzustand
Solid
Farbe
White to Pale Brown
Stabilität:
Hygroscopic
InChIKey
SLAYUXIURFNXPG-CRAIPNDOSA-N
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
HS Code  2941906000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. Sensibilisierung der Atemwege Kategorie 1 Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" /> P261, P285, P304+P341, P342+P311,P501
Sicherheit
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P284 Atemschutz tragen.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P342+P311 Bei Symptomen der Atemwege: GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

Ceforanide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ceforanide is a second generation cephalosporin with good β-lactamase resistance. It has a serum half-life of about three hours, allowing twice-daily dosing.

Verwenden

Ceforanide is a cephalosporin based antibiotic used in the sterilization in various medical procedures.

Definition

ChEBI: A second-generation cephalosporin antibiotic with {[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and 2-(aminomethyl)phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is effective against many col forms, including Escherichia coli, Klebsiella, Enterobacter and Proteus, and most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Ari ona species.

Antimicrobial activity

A semisynthetic parenteral cephalosporin with activity broadly similar to that of cefalotin. Its activity in vitro is significantly reduced in the presence of serum. A 1 g intravenous dose achieves a concentration of c. 135 mg/L at the end of infusion. The response after 0.25, 0.5 and 1 g intravenous doses is essentially linear. A 1 g intramuscular dose produces mean peak values of around 70 mg/L. Plasma protein binding is around 85%.
It is almost entirely eliminated in the urine with a halflife of about 2.5 h, 80–95% being recovered in the first 12 h. The half-life is inversely related to renal function, rising to around 20 h when the creatinine clearance falls below 5 mL/min. About half the dose is removed by hemodialysis over 6 h.
It is generally well tolerated; phlebitis and pain at the site of injection are reported in some patients with occasional transient neutropenia and increased transaminase levels. It has been used principally for the treatment of infections due to Gram-positive cocci, including staphylococcal and streptococcal soft-tissue infections, but is no longer widely available.

Ceforanide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Ceforanide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 87)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29888 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49392 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34571 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167
1026@dideu.com China 8840 58
Finetech Industry Limited
+86-27-87465837 +8618971612321
info@finetechnology-ind.com China 9641 58
changzhou huayang technology co., ltd
+8615250961469
2571773637@qq.com China 9827 58
TargetMol Chemicals Inc.
+1-781-999-5354
support@targetmol.com United States 19973 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43348 58

60925-61-3()Verwandte Suche:


  • CEFORANIDE (200 MG)
  • Ceforanide
  • (6R,7R)-7α-[[(2-Aminomethylphenyl)acetyl]amino]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Antibiotic BL-S-786
  • BL-S-786
  • C06884
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[2-(aMinoMethyl)phenyl]acetyl]aMino]-3-[[[1-(carboxyMethyl)-1H-tetrazol-5-yl]thio]Methyl]-8-oxo-,(6R,7R)-
  • (6R,7R)-7-[[2-[2-(Aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 2-(2,4-Dimethylphenyl)sulf
  • Ceforanide USP/EP/BP
  • (6R,7R)-7-(2-(2-(Aminomethyl)phenyl)acetamido)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Ceforanide (1097807)
  • Bacterial,inhibit,Antibiotic,Inhibitor,Ceforanide
  • 60925-61-3
  • C20H21N7O6S2
  • Ceforanide
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