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Pomalidomide-6-2-2-6-N3

Pomalidomide-6-2-2-6-N3 구조식 이미지

카스 번호:: 2300178-66-7

상품명:: Pomalidomide-6-2-2-6-N3

동의어(영문):: Poma-6-2-2-6-N3;Pomalidomide-6-2-2-6-N3;Pomalidomid-C6-PEG3-butyl-N3;Pomalidomide-C?-PEG?-butyl azide

CBNumber:: CB28363888

분자식:: C29H40N6O8

포뮬러 무게:: 600.67

MOL 파일:: 2300178-66-7.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 9

Pomalidomide-6-2-2-6-N3 속성

저장 조건: 2-8°C

안전

Pomalidomide-6-2-2-6-N3 C화학적 특성, 용도, 생산

용도

Protein degrader builiding block Pomalidomide-C₆-PEG₃-Butyl Azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

Pomalidomide-6-2-2-6-N3 준비 용품 및 원자재

원자재

준비 용품

Pomalidomide-6-2-2-6-N3 공급 업체

글로벌( 9)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Alfa Chemistry		Info@alfa-chemistry.com	United States	24072	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068 +86-15680926068	1924344760@confluore.cn	China	2996	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9929	58
Xi'an Confluore Biological Technology Co., Ltd.	+86-156-80926068 +86-15680926068	1924344760@qq.com	China	4824	58
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1382	58
Zhengzhou convergence chemical co., LTD	0371-0371-55153829 18003835034	2853979819@qq.com	China	9357	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18488	58
Xi‘an Deeptech Biotechnology Co.,LTD	15114901355	15114901355@163.com	China	183	58

Pomalidomide-6-2-2-6-N3 관련 검색:

E3 ligase Ligand-Linker Conjugates 49 Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide 6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid Pomalidomide-C6-PEG3-butyl iodide POMALIDOMIDE-C9-CO2H Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 55 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Pomalidomide-amido-C1-Br Pomalidomide-C6-NH2?hydrochloride Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-