파살마이드
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파살마이드 속성
- 녹는점
- 83-85℃
- 끓는 점
- 389.31°C (rough estimate)
- 밀도
- 1.107
- 굴절률
- 1.5500 (estimate)
- 산도 계수 (pKa)
- pKa (aq soln, 20°) 4.6 ±0.03
안전
파살마이드 C화학적 특성, 용도, 생산
Originator
Parsalmide,Shanghai Lansheng CorporationManufacturing Process
5-Acetylamino-2-acetoxybenzoyl chloride was obtained by reaction of 5acetylamino-2-acetoxy-benzoic acid with thionylchloride.5-Acetylamino-N-butyl-2-hydroxybenzamide was produced in the result of treatment of 5-acetylamino-2-acetoxybenzoyl chloride with butylamine in the presence of sodium hydroxide
5-Acetamino-N-(n-butyl)-2-propargyloxybenzamide was obtained by reaction of 5-acetylamino-N-butyl-2-hydroxybenzamide with propargylbromide in the presence of sodium, isopropyl alcohol and sulfuric acid.
28.8 g (0.1 mole) 5-acetamino-N-(n-butyl)-2-propargyloxybenzamide in 320 ml of 4 N sulfuric acid was heated, under stirring, at 90°-95°C for 2 h. The clear solution was cooled and its pH adjusted to 1 with 1 N NaOH; after filtering, further alkali was subsequently added until a pH of 10 was obtained. At this point the product was separated by filtration and recrystallized from ethanol at 60°C to give 16.6 g (a yield of 68%) of chromatographically pure 5-amino-N-(n-hutyl)-2-propargyloxybenzamide; melting point 85°-87°C.
Therapeutic Function
Muscle relaxant, Antiinflammatory, Analgesic파살마이드 준비 용품 및 원자재
원자재
준비 용품
파살마이드 공급 업체
글로벌( 5)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Shaanxi Didu New Material Co., Ltd | 029-81145920 15353716720 |
1046@dideu.com | China | 9980 | 58 |