ChemicalBook >제품 카탈로그 >CAY10589

CAY10589

CAY10589 구조식 이미지

카스 번호:: 1077626-52-8

상품명:: CAY10589

동의어(영문):: CAY10589;CAY10589 Exclusive;FQMPYBCEABTPIK-UHFFFAOYSA-N;Octanoic acid, 2-[[4-[([1,1'-biphenyl]-4-ylmethyl)amino]-6-chloro-2-pyrimidinyl]thio]-

CBNumber:: CB32590432

분자식:: C25H28ClN3O2S

포뮬러 무게:: 470.03

MOL 파일:: 1077626-52-8.mol

속성

안전

용도

공급 업체 22

CAY10589 속성

끓는 점: 648.1±55.0 °C(Predicted)

밀도: 1.27±0.1 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml

물리적 상태: 결정성 고체

산도 계수 (pKa): 3.04±0.21(Predicted)

안전

CAY10589 C화학적 특성, 용도, 생산

개요

Microsomal Prostaglandin E₂ Synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE₂, which is directly involved in signaling during inflammation, fever and pain. 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs), which are pro-inflammatory mediators. CAY10589 is a dual inhibitor of mPGES-1 (IC₅₀ = 1.3 μM) and 5-LO (IC₅₀ = 1.0 μM). It effectively inhibits PGE₂ and LT synthesis in both cell free and intact cell assays. CAY10589 has minor effects on COX-1 and COX-2, inhibiting these enzymes 34% and 38.8%, respectively, at 10 μM.

CAY10589 준비 용품 및 원자재

원자재

준비 용품

CAY10589 공급 업체

글로벌( 22)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1991	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7984	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8739	58