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CAY10589

CAY10589 Structure
CAY10589 structure
CAS No.
1077626-52-8
Chemical Name:
CAY10589
Synonyms
CAY10589;CAY10589 Exclusive;FQMPYBCEABTPIK-UHFFFAOYSA-N;Octanoic acid, 2-[[4-[([1,1'-biphenyl]-4-ylmethyl)amino]-6-chloro-2-pyrimidinyl]thio]-
CBNumber:
CB32590432
Molecular Formula:
C25H28ClN3O2S
Molecular Weight:
470.03
MDL Number:
MOL File:
1077626-52-8.mol
Last updated:2023-05-21 10:59:17
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CAY10589 Properties

Boiling point 648.1±55.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka 3.04±0.21(Predicted)

CAY10589 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13164 CAY10589 ≥98% 1077626-52-8 1mg $55 2024-03-01 Buy
Cayman Chemical 13164 CAY10589 ≥98% 1077626-52-8 5mg $236 2024-03-01 Buy
Cayman Chemical 13164 CAY10589 ≥98% 1077626-52-8 10mg $420 2024-03-01 Buy
American Custom Chemicals Corporation HCH0069391 2-((4-(((1,1'-BIPHENYL)-4-YLMETHYL)AMINO)-6-CHLORO-2-PYRIMIDINYL)THIO)-OCTANOIC ACID 95.00% 1077626-52-8 5MG $499.99 2021-12-16 Buy
AK Scientific 2947DC 2-[4-Chloro-6-[(4-phenylphenyl)methylamino]pyrimidin-2-yl]sulfanyloctanoicacid 1077626-52-8 10mg $564 2021-12-16 Buy
Product number Packaging Price Buy
13164 1mg $55 Buy
13164 5mg $236 Buy
13164 10mg $420 Buy
HCH0069391 5MG $499.99 Buy
2947DC 10mg $564 Buy

CAY10589 Chemical Properties,Uses,Production

Description

Microsomal Prostaglandin E2 Synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever and pain. 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs), which are pro-inflammatory mediators. CAY10589 is a dual inhibitor of mPGES-1 (IC50 = 1.3 μM) and 5-LO (IC50 = 1.0 μM). It effectively inhibits PGE2 and LT synthesis in both cell free and intact cell assays. CAY10589 has minor effects on COX-1 and COX-2, inhibiting these enzymes 34% and 38.8%, respectively, at 10 μM.

Definition

ChEBI: CAY10589 is a member of biphenyls.

CAY10589 Preparation Products And Raw materials

Raw materials

Preparation Products

CAY10589 Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8618 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Changzhou Furuisi Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
CAY10589 CAY10589 Exclusive FQMPYBCEABTPIK-UHFFFAOYSA-N Octanoic acid, 2-[[4-[([1,1'-biphenyl]-4-ylmethyl)amino]-6-chloro-2-pyrimidinyl]thio]- 1077626-52-8