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ChemicalBook >> CAS DataBase List >> CAY10589

CAY10589

CAY10589 price.
  • $55 - $564
  • Product name: CAY10589
  • CAS: 1077626-52-8
  • MF: C25H28ClN3O2S
  • MW: 470.03
  • EINECS:
  • MDL Number:
  • Synonyms:CAY10589;CAY10589 Exclusive;FQMPYBCEABTPIK-UHFFFAOYSA-N;Octanoic acid, 2-[[4-[([1,1'-biphenyl]-4-ylmethyl)amino]-6-chloro-2-pyrimidinyl]thio]-
5 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
Package
  • 1mg
  • 5MG
  • 10mg
  • ManufacturerAK Scientific
  • Product number2947DC
  • Product description2-[4-Chloro-6-[(4-phenylphenyl)methylamino]pyrimidin-2-yl]sulfanyloctanoicacid
  • Packaging10mg
  • Price$564
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0069391
  • Product description2-((4-(((1,1'-BIPHENYL)-4-YLMETHYL)AMINO)-6-CHLORO-2-PYRIMIDINYL)THIO)-OCTANOIC ACID 95.00%
  • Packaging5MG
  • Price$499.99
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13164
  • Product descriptionCAY10589 ≥98%
  • Packaging1mg
  • Price$55
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13164
  • Product descriptionCAY10589 ≥98%
  • Packaging5mg
  • Price$236
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13164
  • Product descriptionCAY10589 ≥98%
  • Packaging10mg
  • Price$420
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2947DC 2-[4-Chloro-6-[(4-phenylphenyl)methylamino]pyrimidin-2-yl]sulfanyloctanoicacid 10mg $564 2021-12-16 Buy
American Custom Chemicals Corporation HCH0069391 2-((4-(((1,1'-BIPHENYL)-4-YLMETHYL)AMINO)-6-CHLORO-2-PYRIMIDINYL)THIO)-OCTANOIC ACID 95.00% 5MG $499.99 2021-12-16 Buy
Cayman Chemical 13164 CAY10589 ≥98% 1mg $55 2024-03-01 Buy
Cayman Chemical 13164 CAY10589 ≥98% 5mg $236 2024-03-01 Buy
Cayman Chemical 13164 CAY10589 ≥98% 10mg $420 2024-03-01 Buy

Properties

Boiling point :648.1±55.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :3.04±0.21(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Microsomal Prostaglandin E2 Synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever and pain. 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs), which are pro-inflammatory mediators. CAY10589 is a dual inhibitor of mPGES-1 (IC50 = 1.3 μM) and 5-LO (IC50 = 1.0 μM). It effectively inhibits PGE2 and LT synthesis in both cell free and intact cell assays. CAY10589 has minor effects on COX-1 and COX-2, inhibiting these enzymes 34% and 38.8%, respectively, at 10 μM.