ChemicalBook >제품 카탈로그 >N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester

N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester

N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester 구조식 이미지

카스 번호:: 1256490-54-6

상품명:: N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester

동의어(영문):: -deoxy-3’-fluoro-2’N-[[P(S),2’-methyl-P-phenyl-5’-uridylyl]-L-alanine1-MethylethylEster;-O-[(1,1-dimethylethyl)dimethylsilyl]-2’L-Alanine, N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester

CBNumber:: CB36075582

분자식:: C28H43FN3O9PSi

포뮬러 무게:: 643.72

MOL 파일:: 1256490-54-6.mol

속성

안전

용도

공급 업체 4

N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester 속성

밀도: 1.24±0.1 g/cm3(Predicted)

용해도: 에 용해됨클로로포름, 디클로로메탄, 메탄올

산도 계수 (pKa): 9.39±0.10(Predicted)

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 하얀색

안전

N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester C화학적 특성, 용도, 생산

용도

N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester 준비 용품 및 원자재

원자재

준비 용품

N-[[P(S),2''R]-2''-deoxy-3''-O-[(1,1-dimethylethyl)dimethylsilyl]-2''-fluoro-2''-methyl-P-phenyl-5''-uridylyl]-L-alanine 1-Methylethyl Ester 공급 업체

글로벌( 4)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44807	58