파라플루티지드
|
|
파라플루티지드 속성
- 녹는점
- 238-240°
- 끓는 점
- 636.2±65.0 °C(Predicted)
- 밀도
- 1.571±0.06 g/cm3(Predicted)
- 산도 계수 (pKa)
- 8.66±0.40(Predicted)
안전
독성 | LD50 oral in mouse: > 10gm/kg |
---|
파라플루티지드 C화학적 특성, 용도, 생산
Originator
Paraflutizide, Shanghai LanshengManufacturing Process
A mixture of 5.0 g (0.0357 g/mol) of ρ-fluorophenylethyl alcohol, 2.0 g (0.007 g/mol) of 5-chloro-2,4-disulphamylaniline, 2.0 g (0.0068 g/mol) of potassium bichromate and 15 ml of concentrated hydrochloric acid (0.176 g/mol) and 25 ml of water is heated under reflux for 1 h. The mixture is allowed to cool, and 15 ml of ether are added to separate the excess of ρ-fluorophenylethyl alcohol. The aqueous layer is decanted and frozen for 2 h and the precipitate is separated, washed with water and dried in vacuum over phosphoric anhydride. There are collected 1.35 g (yield 47.5%) of the 1,1-dioxide of 3-ρfluorophenyl-methyl-7-sulphamyl-6-chloro-3,4-dihydrobenzo-1,2,4-thiadiazine, which when recrystallised from 30 ml of 50% alcohol on "Norit" active carbon takes the form of a white crystalline substance, melting point is 239°C.Therapeutic Function
Diuretic파라플루티지드 준비 용품 및 원자재
원자재
준비 용품
파라플루티지드 공급 업체
글로벌( 8)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 |
1027@dideu.com | China | 9975 | 58 |
TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 23963 | 58 |