ChemicalBook >제품 카탈로그 >RP-8-브로모-베타-페닐-1,N2-에테노구아노신3',5'-환상모노포스포로티오에이트나트륨염수화물

RP-8-브로모-베타-페닐-1,N2-에테노구아노신3',5'-환상모노포스포로티오에이트나트륨염수화물

RP-8-브로모-베타-페닐-1,N2-에테노구아노신3',5'-환상모노포스포로티오에이트나트륨염수화물 구조식 이미지

카스 번호:: 185246-32-6

한글명:: RP-8-브로모-베타-페닐-1,N2-에테노구아노신3',5'-환상모노포스포로티오에이트나트륨염수화물

동의어(한글):: RP-8-브로모-베타-페닐-1,N2-에테노구아노신3',5'-환상모노포스포로티오에이트나트륨염수화물

상품명:: RP-8-BROMO-BETA-PHENYL-1,N2-ETHENOGUANOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE SODIUM SALT HYDRATE

동의어(영문):: Rp 8 Br PET cGMPS,Rp8BrPETcGMPS;Rp-8-bromo-PET-Cyclic GMPS sodium;Rp-8-bromo-PET-Cyclic GMPS (sodium salt);RP-8-BROMO-BETA-PHENYL-1,N2-ETHENOGUANOSINE 3',5'...;Rp-8-Bromo-β-phenyl-1,N2-ethenoguanosine 3′,5′-cyclic monophosphorothioate;Rp-8-Bromo-beta-phenyl-1,N2-ethenoguanosine 3',5'-cyclic monophosphorothioate sodium salt;RP-8-BROMO-BETA-PHENYL-1,N2-ETHENOGUANOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE SODIUM SALT HYDRATE;Rp-8-Bromo-β-phenyl-1,N2-ethenoguanosine 3μ:5μ-cyclic monophosphorothioate hydrate sodium salt;Rp-8-Bromo-beta-phenyl-1,N2-ethenoguanosine 3',5'-cyclic monophosphorothioate sodium salt >=98% (HPLC), powder;Rp-8-Br-PET-cGMPS hydrate, Rp-β-Phenyl-1,N2-etheno-8-bromoguanosine 3μ,5μ-cyclic monophosphorothioate hydrate sodium salt

CBNumber:: CB3972375

분자식:: C18H14BrN5NaO6PS

포뮬러 무게:: 562.266

MOL 파일:: 185246-32-6.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 22

RP-8-브로모-베타-페닐-1,N2-에테노구아노신3',5'-환상모노포스포로티오에이트나트륨염수화물 속성

녹는점: 240-300 °C(lit.)

저장 조건: -20°C

용해도: H2O: 60°C 이하에서 용해성 15mg/mL

물리적 상태: 가루

색상: 흰색에서 베이지색

안전

안전지침서	22-24/25
WGK 독일	3

RP-8-브로모-베타-페닐-1,N2-에테노구아노신3',5'-환상모노포스포로티오에이트나트륨염수화물 C화학적 특성, 용도, 생산

개요

Rp-8-bromo-PET-Cyclic GMPS (Rp-8-bromo-PET-cGMPS) is an analog of cyclic GMP (cGMP). It is a cell permeable, competitive, and reversible inhibitor of cGMP-dependent protein kinases (cGKs) that blocks activation of cGKI and cGKII by cGMP (K_is = 35 and 30 nM). It less potently inhibits protein kinase A (K_i = 11 μM) and cGMP-induced activation of cyclic nucleotide-gated channels (IC₅₀ = 25 μM). In the absence of cGMP stimulation, Rp-8-bromo-PET-cGMPS can act as a partial agonist of cGKI (K_i = 1 μM). Rp-8-bromo-PET-cGMPS is resistant to hydrolysis by phosphodiesterase 11.

용도

Rp-8-Br-PET-cyclic GMPS Sodium Salt is a competitive inhibitor of cGMP-dependent protein kinase (cGKI).

Biochem/physiol Actions

Rp-8-Br-PET-cGMPS is metabolically stable, competitive inhibitor of cGMP-dependent protein kinase G. Inhibits both PKG I (Ki?=?30 nM) and PKG II and blocks cGMP-gated retinal type ion channels (IC50?=?25 micromoles).

RP-8-브로모-베타-페닐-1,N2-에테노구아노신3',5'-환상모노포스포로티오에이트나트륨염수화물 준비 용품 및 원자재

원자재

준비 용품

RP-8-브로모-베타-페닐-1,N2-에테노구아노신3',5'-환상모노포스포로티오에이트나트륨염수화물 공급 업체

글로벌( 22)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9708	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58