1,8-Bis(dimethylamino)naphthalene
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1,8-Bis(dimethylamino)naphthalene 속성
- 녹는점
- 49-51 °C(lit.)
- 끓는 점
- 144-145°C (3.7505 mmHg)
- 밀도
- 1.12
- 인화점
- >230 °F
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 유기 용매에 용해됩니다.
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 12.1(at 25℃)
- 색상
- 옅은 갈색빛이 도는 핑크색
- 수용성
- 불용성
- 감도
- Light Sensitive
- Merck
- 14,3388
- BRN
- 396782
- InChIKey
- GJFNRSDCSTVPCJ-UHFFFAOYSA-N
- CAS 데이터베이스
- 20734-58-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,C | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36/37/38-34 | ||
안전지침서 | 26-45-36/37/39 | ||
유엔번호(UN No.) | 3259 | ||
WGK 독일 | 3 | ||
F 고인화성물질 | 8-10-23 | ||
위험 등급 | 8 | ||
HS 번호 | 29215900 |
1,8-Bis(dimethylamino)naphthalene C화학적 특성, 용도, 생산
화학적 성질
1,8-Bis(dimethylamino)naphtalene is pale brownish-pink crystalline powder용도
1,8-Bis(dimethylamino)naphthalene, also referred to as protone sponge, is a lipophilic proton trapping agent. 1,8-Bis(dimethylamino)naphthalene is used in the matrix for mass spectroscopy analysis of lipids and fatty acids.일반 설명
Proton-sponge is also referred as 1,8-dimethylamino naphthalene. It is very strong base with weak nucleophilic character due to steric effects. It also participates in the reactions between arachno-6,9-C2B8H14 and selected acyl chlorides. It has been tested as an effective H+ scavenger.Solubility in organics
Soluble in most organic solvents, such as methanol and chloroform.Purification Methods
It is prepared by methylating 1,8-diaminonaphthalene, and likely impurities are methylated products. The tetramethyl compound is a stronger base than the unmethylated, di and trimethylated derivatives. The pKa values are: 1,8-(NH2)2 = 4.61, 1,8-(NHMe)2 = 5.61, 1-NHMe-8-NHMe2 = 6.43 and 1,8-(NMe2)2 = 12.34. The mixture is then treated with H2O at pH 8 (where all but the required base are protonated) and extracted with Et2O or CHCl3. The dried extract (K2CO3) yields the tetramethyldiamine on evaporation which can be distilled. It is a strong base with weak nucleophilic properties, e.g. it could not be alkylated by refluxing with EtI in MeCN for 4 days; and on treatment with methyl fluorosulfonate only the fluorosulfonate salt of the base is obtained. [NMR: Adler et al. J Chem Soc, Chem Commun 723 1968, Brown & Letang J Am Chem Soc 63 358 1941, Brzezinski et al. J Chem Soc Perkin Trans 2 857 1991.] Alternatively, crystallise proton sponge from EtOH and dry it in a vacuum oven. Store it in the dark in a CO2-free atmosphere. [Benoit et al. Can J Chem 65 996 1987, Beilstein 13 IV 344.]1,8-Bis(dimethylamino)naphthalene 준비 용품 및 원자재
원자재
준비 용품
1,8-Bis(dimethylamino)naphthalene 공급 업체
글로벌( 311)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Nanjing Fred Technology Co., Ltd | +86-25-84696168 +86-15380713688 |
Austin@fredbio.com | China | 2449 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 18223 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32686 | 60 |
Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 |
sales@ansciepchem.com | CHINA | 4242 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10247 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
1,8-Bis(dimethylamino)naphthalene 관련 검색:
염산 메트포르민 P-다이메틸아미노벤즈알데하이드 3-(디메틸아미노)프로필아민 히드라진 4-다이메틸아미노피리딘 4-다이메틸아미노벤조산 1,8-디아미노나프탈렌 2-디메틸아미노에탄올
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1,8-Bis(dimethylamino)naphthalene
SPONGE
6,7-BIS(DIMETHYLAMINO)-1,3-BIS(TRIFLUOROMETHYL)-1H,3H-BENZO[DE]ISOCHROMENE-1,3-DIOL
1,8-BIS(DIMETHYLAMINO)NAPHTHALENE HYDROCHLORIDE
2-{[4,5-BIS(DIMETHYLAMINO)-1-NAPHTHYL]METHYLENE}MALONAMIDE