황산 스트렙토마이신
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황산 스트렙토마이신 속성
- 녹는점
- >185°C (dec.)
- 알파
- -79~-88°(20℃/D)(c=1,H2O)(calculated on the dried basis)
- 밀도
- 1.2302 (rough estimate)
- 굴절률
- -85 ° (C=1, H2O)
- 저장 조건
- 2-8°C
- 용해도
- H2O: 0.1 g/mL, 투명
- 물리적 상태
- 가루
- 색상
- 흰색에서 황백색까지
- 수소이온지수(pH)
- pH (100g/l, 25℃) : 4.5~7.0
- 수용성
- 18&C에서 >=0.01g/100mL
- Merck
- 14,8826
- BRN
- 3894995
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- InChIKey
- QTENRWWVYAAPBI-YZTFXSNBSA-N
- LogP
- -1.523 (est)
- CAS 데이터베이스
- 3810-74-0
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36/37/38-63-42/43 | ||
안전지침서 | 26-36-36/37-45-22-60 | ||
WGK 독일 | 3 | ||
RTECS 번호 | WK4990000 | ||
F 고인화성물질 | 3 | ||
TSCA | Yes | ||
HS 번호 | 29412000 | ||
기존화학 물질 | KE-09605 |
황산 스트렙토마이신 C화학적 특성, 용도, 생산
개요
Streptomycin was found in the culture broth of Streptomyces griseus by S. A. Waksman of Rutgers University in 1944; it was the second antibiotic introduced clinically (after penicillin). This drug is a water soluble, basic substance having an aminoglycoside structure and showing strong activity against a wide range of gram-positive and gram-negative bacteria including Mycobacterium. Streptomycin is the first choice among antituberculotic antibiotics and has been used for the therapy of Spirochaeta and Treponema infections.화학적 성질
White to off-white powder용도
Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor. Streptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis.일반 설명
An antibacterial. White to light gray or pale buff powder with faint amine-like odor.공기와 물의 반응
Hygroscopic. Water soluble.반응 프로필
Streptomycin sulfate is a medicinal amino saccharide.건강위험
SYMPTOMS: Symptoms of exposure to Streptomycin sulfate include skin rashes, eosinophilia, blood dyscrasias, stomatitis, anaphylactic shock, pruritus, scaling, and fever.화재위험
Flash point data for Streptomycin sulfate are not available, however Streptomycin sulfate is probably combustible.Safety Profile
Poison by ingestion and intravenous routes. Moderately toxic by subcutaneous route. An experimental teratogen. Human systemic effects by intraperitoneal route: flaccid paralysis without anesthesia, motor activity changes and pulmonary changes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also STREPTOMYCIN and SULFATES.Purification Methods
The sulfate is recrystallised from H2O/EtOH, washed with a little EtOH, Et2O and dried in a vacuum. [UV and IR: Grove & Randall Antibiotics Monographs 2 163 1855, Heuser et al. J Am Chem Soc 75 4013 1953, Kuehl et al. J Am Chem Soc 68 1460 1946, Regna et al. J Biol Chem 165 631 1946.] During protein synthesis it inhibits initiation and causes misreading of mRNA [Zierhut et al. Eur J Biochem 98 577 1979, Chandra & Gray Methods Enzymol 184 70 1990]. [Beilstein 18/11 V 82.]황산 스트렙토마이신 준비 용품 및 원자재
원자재
준비 용품
황산 스트렙토마이신 공급 업체
글로벌( 612)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5895 | 58 |
shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 |
sales@sdperfect.com | China | 294 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 |
hbjbtech@163.com | China | 1000 | 58 |
Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 |
admin@hbsaisier.cn | China | 1009 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 |
sarah@tnjone.com | China | 1143 | 58 |
Apeloa production Co.,Limited | +8619933239880 |
admin@apcl.com.cn | China | 853 | 58 |
Hebei Longbang Technology Co., LTD | +86-18032476855 +86-18032476855 |
admin@hblongbang.com | China | 942 | 58 |
HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 +86-18532138899 |
L18532138899@163.com | China | 931 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |