KIN1408

KIN1408 구조식 이미지
카스 번호:
1903800-11-2
상품명:
KIN1408
동의어(영문):
KIN1408;KIN-1408 (KIN-1408;KIN1408 >=98% (HPLC);8-Quinolinol, 7-[[4-(difluoromethoxy)phenyl][(5-methoxy-2-benzothiazolyl)amino]methyl]-;7-((4-(difluoromethoxy)phenyl)((5-methoxybenzo[d]thiazol-2-yl)amino)methyl)quinolin-8-ol);KIN-1408;KIN 1408;7-((4-(DIFLUOROMETHOXY)PHENYL)((5-METHOXYBENZO[D]THIAZOL-2-YL)AMINO)METHYL)QUINOLIN-8-OL
CBNumber:
CB43121111
분자식:
C25H19F2N3O3S
포뮬러 무게:
479.5
MOL 파일:
1903800-11-2.mol
MSDS 파일:
SDS

KIN1408 속성

끓는 점
675.6±65.0 °C(Predicted)
밀도
1.430±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO:34.5(Max Conc. mg/mL);71.95(Max Conc. mM)
물리적 상태
고체
산도 계수 (pKa)
4.22±0.50(Predicted)
색상
Light yellow to yellow

안전

KIN1408 C화학적 특성, 용도, 생산

개요

KIN1408 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. It induces interferon regulatory factor 3 (IRF3) activation and translocation into the nucleus in a concentration-dependent manner in HEK293 cells without inducing cellular toxicity. KIN1408 induces expression of the innate immune genes MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells stimulated with phorbol 12-myristate 12-acetate (PMA; ). It exhibits concentration-dependent broad-spectrum antiviral activity against dengue virus 2 as well as the influenza A, Ebola, Nipah, and Lassa viruses.

KIN1408 준비 용품 및 원자재

원자재

준비 용품


KIN1408 공급 업체

글로벌( 26)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6313 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
MedChemexpress LLC 021-58955995
sales@medchemexpress.cn United States 4863 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9707 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088
3193328036@qq.com China 29786 68
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720
psaitong@jm-bio.com China 12308 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312
liming@bio-fount.com China 9730 58
DC Chemicals 021-58447131 13564518121
sales@dcchemicals.com China 9412 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946
1461866103@qq.com China 16111 58

Copyright 2019 © ChemicalBook. All rights reserved