ChemicalBook >> CAS DataBase List >>KIN1408

KIN1408

CAS No.
1903800-11-2
Chemical Name:
KIN1408
Synonyms
KIN1408;KIN-1408 (KIN-1408;KIN1408 >=98% (HPLC);8-Quinolinol, 7-[[4-(difluoromethoxy)phenyl][(5-methoxy-2-benzothiazolyl)amino]methyl]-;7-((4-(difluoromethoxy)phenyl)((5-methoxybenzo[d]thiazol-2-yl)amino)methyl)quinolin-8-ol);KIN-1408;KIN 1408;7-((4-(DIFLUOROMETHOXY)PHENYL)((5-METHOXYBENZO[D]THIAZOL-2-YL)AMINO)METHYL)QUINOLIN-8-OL
CBNumber:
CB43121111
Molecular Formula:
C25H19F2N3O3S
Molecular Weight:
479.5
MDL Number:
MOL File:
1903800-11-2.mol
Last updated:2024-07-02 08:55:08

KIN1408 Properties

Boiling point 675.6±65.0 °C(Predicted)
Density 1.430±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:34.5(Max Conc. mg/mL);71.95(Max Conc. mM)
form A solid
pka 4.22±0.50(Predicted)
color Light yellow to yellow

KIN1408 price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21790 KIN1408 ≥98% 1903800-11-2 5mg $93 2024-03-01 Buy
Cayman Chemical 21790 KIN1408 ≥98% 1903800-11-2 10mg $176 2024-03-01 Buy
ChemScene CS-5477 KIN1408 99.55% 1903800-11-2 1mg $180 2021-12-16 Buy
AK Scientific 2008EG 7-[[4-(Difluoromethoxy)phenyl]-[(5-methoxy-1,3-benzothiazol-2-yl)amino]methyl]quinolin-8-ol 1903800-11-2 5mg $201 2021-12-16 Buy
ChemScene CS-5477 KIN1408 99.55% 1903800-11-2 5mg $420 2021-12-16 Buy
Product number Packaging Price Buy
21790 5mg $93 Buy
21790 10mg $176 Buy
CS-5477 1mg $180 Buy
2008EG 5mg $201 Buy
CS-5477 5mg $420 Buy

KIN1408 Chemical Properties,Uses,Production

Description

KIN1408 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. It induces interferon regulatory factor 3 (IRF3) activation and translocation into the nucleus in a concentration-dependent manner in HEK293 cells without inducing cellular toxicity. KIN1408 induces expression of the innate immune genes MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells stimulated with phorbol 12-myristate 12-acetate (PMA; ). It exhibits concentration-dependent broad-spectrum antiviral activity against dengue virus 2 as well as the influenza A, Ebola, Nipah, and Lassa viruses.

KIN1408 Preparation Products And Raw materials

Raw materials

Preparation Products

KIN1408 Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29786 68
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9412 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946 1461866103@qq.com China 16111 58
KIN1408 7-((4-(difluoromethoxy)phenyl)((5-methoxybenzo[d]thiazol-2-yl)amino)methyl)quinolin-8-ol) KIN-1408 (KIN-1408 KIN-1408;KIN 1408;7-((4-(DIFLUOROMETHOXY)PHENYL)((5-METHOXYBENZO[D]THIAZOL-2-YL)AMINO)METHYL)QUINOLIN-8-OL 8-Quinolinol, 7-[[4-(difluoromethoxy)phenyl][(5-methoxy-2-benzothiazolyl)amino]methyl]- KIN1408 >=98% (HPLC) 1903800-11-2 C25H19F2N3O3S