KIN1408
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- $93 - $2520
- Product name: KIN1408
- CAS: 1903800-11-2
- MF: C25H19F2N3O3S
- MW: 479.5
- EINECS:
- MDL Number:
- Synonyms:KIN1408;7-((4-(difluoromethoxy)phenyl)((5-methoxybenzo[d]thiazol-2-yl)amino)methyl)quinolin-8-ol);KIN-1408 (KIN-1408;KIN-1408;KIN 1408;7-((4-(DIFLUOROMETHOXY)PHENYL)((5-METHOXYBENZO[D]THIAZOL-2-YL)AMINO)METHYL)QUINOLIN-8-OL;8-Quinolinol, 7-[[4-(difluoromethoxy)phenyl][(5-methoxy-2-benzothiazolyl)amino]methyl]-;KIN1408 >=98% (HPLC)
13 prices
Selected condition：
Brand
- AK Scientific
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number2008EG
- Product description7-[[4-(Difluoromethoxy)phenyl]-[(5-methoxy-1,3-benzothiazol-2-yl)amino]methyl]quinolin-8-ol
- Packaging5mg
- Price$201
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611452
- Product descriptionKIN-1408
- Packaging5mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611452
- Product descriptionKIN-1408
- Packaging10mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611452
- Product descriptionKIN-1408
- Packaging50mg
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21790
- Product descriptionKIN1408 ≥98%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21790
- Product descriptionKIN1408 ≥98%
- Packaging10mg
- Price$176
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5477
- Product descriptionKIN1408 99.55%
- Packaging1mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5477
- Product descriptionKIN1408 99.55%
- Packaging5mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5477
- Product descriptionKIN1408 99.55%
- Packaging10mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5477
- Product descriptionKIN1408 99.55%
- Packaging50mg
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5477
- Product descriptionKIN1408 99.55%
- Packaging100mg
- Price$2520
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC22553
- Product descriptionKIN-1408 >98%
- Packaging10mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC22553
- Product descriptionKIN-1408 >98%
- Packaging50mg
- Price$1200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2008EG | 7-[[4-(Difluoromethoxy)phenyl]-[(5-methoxy-1,3-benzothiazol-2-yl)amino]methyl]quinolin-8-ol | 5mg | $201 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611452 | KIN-1408 | 5mg | $569.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611452 | KIN-1408 | 10mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611452 | KIN-1408 | 50mg | $1802 | 2021-12-16 | Buy |
| Cayman Chemical | 21790 | KIN1408 ≥98% | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 21790 | KIN1408 ≥98% | 10mg | $176 | 2024-03-01 | Buy |
| ChemScene | CS-5477 | KIN1408 99.55% | 1mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-5477 | KIN1408 99.55% | 5mg | $420 | 2021-12-16 | Buy |
| ChemScene | CS-5477 | KIN1408 99.55% | 10mg | $600 | 2021-12-16 | Buy |
| ChemScene | CS-5477 | KIN1408 99.55% | 50mg | $1800 | 2021-12-16 | Buy |
| ChemScene | CS-5477 | KIN1408 99.55% | 100mg | $2520 | 2021-12-16 | Buy |
| DC Chemicals | DC22553 | KIN-1408 >98% | 10mg | $400 | 2021-12-16 | Buy |
| DC Chemicals | DC22553 | KIN-1408 >98% | 50mg | $1200 | 2021-12-16 | Buy |
Properties
Boiling point :675.6±65.0 °C(Predicted)
Density :1.430±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:34.5(Max Conc. mg/mL);71.95(Max Conc. mM)
form :A solid
pka :4.22±0.50(Predicted)
color :Light yellow to yellow
Density :1.430±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:34.5(Max Conc. mg/mL);71.95(Max Conc. mM)
form :A solid
pka :4.22±0.50(Predicted)
color :Light yellow to yellow
Safety Information
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Description
KIN1408 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. It induces interferon regulatory factor 3 (IRF3) activation and translocation into the nucleus in a concentration-dependent manner in HEK293 cells without inducing cellular toxicity. KIN1408 induces expression of the innate immune genes MDA5, RIG-1, Mx1, IRF7, and IFIT1 in THP-1 cells stimulated with phorbol 12-myristate 12-acetate (PMA; ). It exhibits concentration-dependent broad-spectrum antiviral activity against dengue virus 2 as well as the influenza A, Ebola, Nipah, and Lassa viruses.Suppliers and manufacturers
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Aladdin Scientific
MedChemexpress LLC
Shanghai EFE Biological Technology Co., Ltd.
Beijing Solarbio Science & Tecnology Co., Ltd.
Beijing Jin Ming Biotechnology Co., Ltd.
Fan De(Beijing) Biotechnology Co., Ltd.
DC Chemicals
Beijing xinyanhui pharmaceutical research and development co., LTD