The acute oral LD50 value in rats was reported as 1.65 g/kg (1.47-1.83 g/ kg) (Moreno, 1972a). The acute dermal LD50 value in rabbits was reported as > 5 g/kg (Moreno, 1972b).
Reported found in Melilotus officinalis, from which it may be extracted by water distillation.
정의
ChEBI: A chromanone that is the 3,4-dihydro derivative of coumarin.
제조 방법
Dihydrocoumarin is synthesized by reduction of coumarin under pressure in the presence of nickel at 160 to 200°C or in the presence of Pd-BaSO4 in alcoholic solution.
일반 설명
White to pale yellow clear oily liquid with a sweet odor. Solidifies around room temperature.
공기와 물의 반응
Solutions of the chemical in water are stable for less than two hours. Insoluble in water.
반응 프로필
Hydrocoumarin is a lactone (behaves as an ester). Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Hydrocoumarin may hydrolyze under alkaline or acidic conditions.
