1,2-BIS[(디메틸아미노)디메틸실]에탄
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1,2-BIS[(디메틸아미노)디메틸실]에탄 속성
- 끓는 점
- 101-103 °C13 mm Hg(lit.)
- 밀도
- 0.824 g/mL at 25 °C(lit.)
- 굴절률
- n
20/D 1.446(lit.)
- 인화점
- 57 °F
- 산도 계수 (pKa)
- 10.31±0.70(Predicted)
- 물리적 상태
- 투명한 액체
- 색상
- 무색 내지 거의 무색
- Specific Gravity
- 0.824
- Hydrolytic Sensitivity
- 8: reacts rapidly with moisture, water, protic solvents
- BRN
- 4366167
- CAS 데이터베이스
- 91166-50-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F,C | ||
---|---|---|---|
위험 카페고리 넘버 | 11-34 | ||
안전지침서 | 16-26-36/37/39-45 | ||
유엔번호(UN No.) | UN 2924 3/PG 2 | ||
WGK 독일 | 3 | ||
F 고인화성물질 | 10-21 | ||
TSCA | No | ||
위험 등급 | 3.1 | ||
포장분류 | II | ||
HS 번호 | 29319019 |
1,2-BIS[(디메틸아미노)디메틸실]에탄 C화학적 특성, 용도, 생산
물리적 성질
bp 100–103°C/13 mmHg; d 0.824 g cm?3.용도
1,4-Bis(dimethylamino)-1,1,4,4-tetramethyldisilethylene is used as a reagent for the protection of primary amines with lower pKa values, such as substituted anilines, as their tetramethyldisilylazacyclopentane or Stabase adduct; precursor of tetramethyldisilylthiacyclopentane, a sulfur transfer reagent.The title reagent is used for the preparation of Stabase derivatives of primary amines, and is particularly useful for the protection of primary aromatic amines with pKa values of 10–11. The protection of substituted anilines is achieved by heating equimolar amounts of the title compound and the anilines in the presence of zinc iodide (0.5 mol %) under a slow stream of nitrogen at 140°C for 5 h. In many cases the products can be purified by vacuum distillation. Cleavage of the Stabase adducts to the corresponding primary amines can be performed in ether in the presence of 2 equiv of methanol and a small amount of p-toluenesulfonic acid monohydrate (0.2 mol %). The tetramethyldisilylazacyclopentane or Stabase adduct (3) is a particularly attractive protecting group due to its ease of preparation, base stability, and facile removal (eq 1).
제조 방법
the reagent is prepared as a colorless liquid in 90% yield by treating commercially available bis(chlorodimethylsilyl) ethane with 5 equiv of dimethylamine in ether at 0°C for 5 h.1,2-BIS[(디메틸아미노)디메틸실]에탄 준비 용품 및 원자재
원자재
준비 용품
1,2-BIS[(디메틸아미노)디메틸실]에탄 공급 업체
글로벌( 74)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 16914 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29894 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
WinWin Chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 |
sales@win-winchemical.com | China | 14278 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52861 | 58 |
Alfa Chemistry | |
Info@alfa-chemistry.com | United States | 24072 | 58 |
Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 |
cbc@coresyn.com | China | 9991 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20294 | 58 |
1,2-BIS[(디메틸아미노)디메틸실]에탄 관련 검색:
에탄 노르말트리메틸실릴디메틸아민
1,2-DICHLOROTETRAMETHYLDISILANE
1,2-BIS(TRIMETHOXYSILYL)DECANE
1,2-BIS(PENTAMETHYLDISILOXANYL)ETHANE
DIVINYLTETRAMETHYLDISILANE
1,2-Bis(triethoxysilyl)ethane
1,2-BIS(TRIMETHOXYSILYL)ETHANE
1,2-BIS(METHYLDIETHOXYSILYL)ETHYLENE
1,2-Bis(dimethylsilyl)benzene
1,2-DIMETHYL-1,1,2,2-TETRAPHENYLDISILANE
1,2-DIMETHOXY-1,1,2,2-TETRAMETHYLDISILANE
Bis(trimethylsilyl)trifluoroacetamide
DIMETHYLSILYLDIMETHYLAMINE
1,2-BIS[(DIMETHYLAMINO)DIMETHYLSILYL]ETHANE
1,1,4,4-TETRAMETHYLDISILETHYLENE
1,2-ETHANEDIYLBIS(METHYLSILANE)
1,4-DISILABUTANE