NS 3694
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NS 3694 속성
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 22mg/mL,에 용해됨
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- Off-white to light yellow
안전
WGK 독일 | 3 |
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NS 3694 C화학적 특성, 용도, 생산
개요
Cytochrome c, which leaks from the mitochondrial intermembrane space into the cytosol, causes oligomerization of apoptotic protease-activating factor 1 (Apaf-1), forming a caspase activation complex known as the apoptosome. NS3694 is a cell-permeable diarylurea compound that inhibits apoptosome formation and caspase activation. It blocks cytochrome c-induced caspase activation in HeLa cell cytosolic extracts with an IC50 value of approximately 50 μM. NS3694 prevents the formation of apoptosomes, which prevents the association of procaspases with Apaf-1. It suppresses caspase activation and apoptosis in cells treated with either TNF-α or staurosporine . NS3694 is used to examine the role of apoptosome-mediated caspase activation in cell death.용도
NS3694 is a suppressor of the formation of apoptosome Apaf-1.NS 3694 준비 용품 및 원자재
원자재
준비 용품
NS 3694 공급 업체
글로벌( 28)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30250 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
VDM Biochemicals | 0330-2528181 |
sales@vdmbio.com | United States | 510 | 64 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9707 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing@energy-chemical.com | China | 44941 | 58 |
InvivoChem | 13549236410 |
sales@invivochem.cn | China | 6755 | 58 |
TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 23963 | 58 |