클로페존 C화학적 특성, 용도, 생산
Originator
Perclusone,Anphar-Rolland,France,1967
Manufacturing Process
935 g of phenylbutazone are dissolved, with heating to a lukewarm state, in
2.7 liters of acetone containing 20% water, and the mixture is filtered if
necessary. 853.5 g of p-chlorophenoxyacetic acid diethylamino ethylamide are
dissolved in 300 cc of acetone containing 20% water, and the solution is
poured into the phenylbutazone solution. There is slight heating, and the
solution clarifies. The salt crystallizes rapidly. Drying is effected on a Buchner
funnel and the mixture is washed in 450 cc of acetone containing 20% of
water. The 1,702 g of product obtained is recrystallized in 2,450 cc of acetone
containing 20% of water and, after drying in an oven at 37°C, 1,585 g (86%)
of product are obtained. The product is in the form of a white crystalline
powder having a melting point of from 87° to 89°C in the Maquenne block.
Therapeutic Function
Analgesic, Antiinflammator
클로페존 준비 용품 및 원자재
원자재
준비 용품
