Endothelin-1 (human, porcine)
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Endothelin-1 (human, porcine) 속성
- 끓는 점
- 2467.3±65.0 °C(Predicted)
- 밀도
- 1.273±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- 용해도
- 1% 아세트산: >1mg/mL
- 물리적 상태
- 가루
- 색상
- 하얀색
- 수용성
- 물에 용해됩니다.
- Merck
- 13,3610
- InChIKey
- ZUBDGKVDJUIMQQ-UHFFFAOYSA-N
안전
WGK 독일 | 3 | ||
---|---|---|---|
RTECS 번호 | KE9446500 | ||
F 고인화성물질 | 3-10 | ||
HS 번호 | 2937190000 |
Endothelin-1 (human, porcine) C화학적 특성, 용도, 생산
용도
Endothelin-1 (human, porcine) has been used for coating wells in polystyrene ELISA plates. Potent agonist for ETA and ETB endothelia receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.주요 응용
Endothelin-1 (human, porcine) has been used:to study its effects on the production of erythropoietin under normoxia and carbon monoxide-induced hypoxia in rat models.
as a protein kinase C (PKC) agonist to study its effects on the phosphorylation of myofilament proteins in rat myocytes.
to induce a hypertrophic-like state to study its effects on contraction pressure in normal and mutated human induced pluripotent stem cells (hiPSC)-derived cardiomyocytes.
in vitro hydrolysis products of macroendothelin-1, a precursor of endothelin-1, and their pharmacodynamic properties in rabbits.
as a receptor for endothelin-1 and its role in G protein-mediated signal transduction Research.
Biological Functions
Endothelins are a family of vasoactive peptides secreted by endothelial cells. The three major endothelin peptides are all composed of 21 amino acids. Endothelins are the most potent vasoconstrictors known. Contraction of vascular smooth muscle in response to endothelin is associated with an increase in intracellular calcium. Increases in endothelin levels have been reported in patients with vasospastic, hypoxic, and ischemic diseases.The two identified isoforms of endothelin receptors have differing affinity for the three endothelin peptides. Selective and nonselective endothelin receptor antagonists are in development for potential use in the treatment of hypertension and other disorders associated with increased vascular resistance.Biochem/physiol Actions
Potent agonist for ETA and ETB endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.Endothelin-1 (human, porcine) 준비 용품 및 원자재
원자재
준비 용품
Endothelin-1 (human, porcine) 공급 업체
글로벌( 175)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21663 | 55 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10311 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
Cellmano Biotech Limited | 0551-65326643 18156095617 |
info@cellmano.com | China | 999 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29821 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 13392 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
Endothelin-1 (human, porcine) 관련 검색:
이노시톨 장미 벵갈 나트륨
BIG ET-1 (1-38) (HUMAN)
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
IRL-1038
Octreotide
ENDOTHELIN (16-21)
ENDOTHELIN-3 (HUMAN) (PORCINE, RAT, RABBIT)
ET-1(Endothelin-1)
BQ-3020
Endothelin-1 (human, porcine)
GLYCYL-L-TRYPTOPHAN
H-VAL-TRP-OH
H-ILE-TRP-OH
ENDOTHELIN-3 (HUMAN) (PORCINE, RAT, RABBIT)
H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
H-GLY-GLY-TRP-OH
FLUORESCEIN-ENDOTHELIN 1 HUMAN