ChemicalBook >제품 카탈로그 >생화학 공학>아미노산과 유도체>프롤린 유도체>(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 구조식 이미지

카스 번호:: 114676-69-6

상품명:: (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

동의어(영문):: (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;N-Boc-cis-D-Hyp-Ome;CIS-1-BOC-4-HYDROXY-D-PROLINATE;Methyl cis-1-Boc-4-hydroxy-D-prolinate;Boc-cis-4-Hydroxy-D-proline methyl ester;N-Boc-cis-4-hydroxy-D-proline methyl ester;1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate;Boc-Cis-D-Hyp-OMe;cis-Boc-d-Hyp-Ome;(2R,4R)-1-Boc-4-hydroxypyrroL

CBNumber:: CB51118684

분자식:: C11H19NO5

포뮬러 무게:: 245.27

MOL 파일:: 114676-69-6.mol

속성

안전

용도

공급 업체 202

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 속성

녹는점: 76 °C

끓는 점: 335.2±42.0 °C(Predicted)

알파: 63° (C=1,EtOH)

밀도: 1.216±0.06 g/cm3(Predicted)

저장 조건: Sealed in dry,Store in freezer, under -20°C

산도 계수 (pKa): 14.27±0.40(Predicted)

물리적 상태: 가루

색상: 하얀색

InChI: InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8-/m1/s1

InChIKey: MZMNEDXVUJLQAF-HTQZYQBOSA-N

SMILES: N1(C(OC(C)(C)C)=O)C[C@H](O)C[C@@H]1C(OC)=O

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

HS 번호	2933998090

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P304+P340	흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P405	밀봉하여 저장하시오.

NFPA 704

	1
2		0

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate C화학적 특성, 용도, 생산

용도

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate (N-Boc-cis-4-hydroxy-D-proline methyl ester) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 준비 용품 및 원자재

원자재

준비 용품

1-Pyrrolidinecarboxylicacid,4-amino-2-methyl-,1,1-dimethylethylester,(2S-trans)-(9CI) 메틸(R)-1-Boc-4,4-디플루오로피롤리딘-2-카르복실레이트 1,2-Pyrrolidinedicarboxylic acid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 공급 업체

글로벌( 202)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ZhengZhou Yimi Pharma R&D Co.,LTD.	15393710992	375000787@QQ.com	China	22	58
Shanghai Xinxin Pharmaceutical Technology Co., Ltd.	13671725141	hickle@yeah.net	China	768	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Sichuan Tongsheng Amino acids Co.,Ltd.	0838-2274206 17340404235	sales@biots.cn	China	300	66
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44852	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078	sales@jingyan-chemical.com	China	9963	60
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 관련 검색:

CIS-디클로로비스(2,2'-비피리딘)루테늄(II)이수화물,99 (R)-(+)-2-(메톡시메틸)-1-피롤리딘카르복살데하이드 METHYL-RN-(메톡시카르보닐)-프롤린에스테르 2-TERT-BUTOXYCARBONYLAMINO-4-HYDROXY-BUTYRICACIDMETHYL에스테르 (S)-1-BOC-2-메틸피롤리딘 Cis-4-Cyclohexylcyclohexanol (2S,3R)-3-Hydroxyproline (+)-CIS-(2R,3S)-3-Hydroxyproline cis-cyclopropanecarboxylic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester cis-2-(Ethoxycarbonyl)cyclopropanecarboxylic acid cis-cyclopentane-1,2-diamine dihydrochloride tert-butyl (cis-3-aminocy... (1s,3s)-methyl 3-aminocyclobutane carboxylate hydrochloride (2S,3R)-methyl 3-hydroxypyrrolidine-2-carboxylate hydrochloride (1S,2S)-2-fluorocyclopropanecarboxylic acid cis-3-Hydroxycyclobutanecarboxylic acid rel-(4aR,7aR)-6-Benzyloctahydro-1H-pyrrolo[3,4-b]pyridine Cyclopropanecarboxylicacid,2-amino-,cis-(9CI)