ChemicalBook >제품 카탈로그 >BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-

BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-

BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)- 구조식 이미지

카스 번호:: 950736-05-7

상품명:: BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-

동의어(영문):: CS-1184;MDK36057;RAF-IN-10n;B-Raf IN 1;B-Raf inhibit 1;B-Raf IN 1, >=98%;Raf kinases,B-Raf IN 1,BRaf IN 1,Inhibitor,B Raf IN 1,Raf,inhibit;N-(3-(3-(4-((diMethylaMino)Methyl)phenyl)pyrazolo[1,5-a]pyriMidin-7-yl)phenyl)-3-(trifluoroMethyl)benzaMide;BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-

CBNumber:: CB52668351

분자식:: C29H24F3N5O

포뮬러 무게:: 515.53

MOL 파일:: 950736-05-7.mol

속성

안전

용도

공급 업체 64

BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)- 속성

밀도: 1.28±0.1 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMF: 14 mg/ml; DMSO: 33 mg/ml; Ethanol: 1 mg/ml

산도 계수 (pKa): 12.75±0.70(Predicted)

물리적 상태: 가루

색상: Light yellow to yellow

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

HS 번호	2934999090

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고		P264, P270, P301+P312, P330, P501

예방조치문구:

P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)- C화학적 특성, 용도, 생산

개요

B-RAF IN 1 is an inhibitor of B-RAF (IC₅₀ = 24 nM) that also inhibits C-RAF (IC₅₀ = 25 nM). It is selective over 13 other kinases, including PKCα, IKKβ, and PI3Kα, at concentrations greater than 2 μM, but does inhibit p38α and CAMKII (IC₅₀s = 216 and 822 nM, respectively). B-RAF IN 1 binds to B-RAF in the inactive conformation based on co-crystallization with the wild-type enzyme. It inhibits proliferation of WM 266-4 and HT29 cells with IC₅₀ values of 920 and 780 nM, respectively.

용도

N-[3-[3-[4-[(Dimethylamino)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)benzamide is a potent and selective B-Raf inhibitor.

BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)- 준비 용품 및 원자재

원자재

준비 용품

BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)- 공급 업체

글로벌( 64)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32820	60
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29815	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32038	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7552	61
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4861	58
Shanghai JiYi Biotechnology Co. Ltd.	13621943973	sales@shjiyipharmatech.com	China	1166	55

BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)- 관련 검색:

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