NSC5844

NSC5844 구조식 이미지
카스 번호:
140926-75-6
상품명:
NSC5844
동의어(영문):
RE640;RE 640;RE-640;NSC5844;NSC5844 (RE640);NSC 5844; NSC-5844; RE 640; RE-640; RE640;N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine;1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)-;NSC 5844,RE640,NSC5844,inhibit,Inhibitor,RE 640,Parasite,NSC-5844
CBNumber:
CB53121123
분자식:
C20H16Cl2N4
포뮬러 무게:
383.27
MOL 파일:
140926-75-6.mol

NSC5844 속성

끓는 점
632.6±55.0 °C(Predicted)
밀도
1.431±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: 0.33 mg/ml; DMSO: 0.25 mg/ml; Ethanol: slightly soluble
물리적 상태
결정성 고체
산도 계수 (pKa)
6.61±0.50(Predicted)
색상
White to off-white

안전

NSC5844 C화학적 특성, 용도, 생산

개요

NSC 5844 is a bis-quinoline with diverse biological activities. It inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine in vitro (IC50s = 17 and 27 nM, respectively) but lacks activity against P. berghei in vivo. NSC 5844 inhibits the growth of MDA-MB-468 and MCF-7 breast cancer cells with GI50 values of 7.35 and 14.80 μM, respectively. It also inhibits 24% of botulinum neurotoxin serotype A light chain (BoNT/A LC) metalloprotease activity at a concentration of 20 μM.

NSC5844 준비 용품 및 원자재

원자재

준비 용품


NSC5844 공급 업체

글로벌( 70)공급 업체
공급자 전화 이메일 국가 제품 수 이점
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32760 60
InvivoChem
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sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc.
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support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054
trendseenbio@gmail.com China 11681 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20313 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57511 58
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139
orders@jknbiochem.com China 4692 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131980 58
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
sales@rechemscience.com China 2981 58
Grader reagent 18221735425
sales@xinpingchem.com China 9951 58

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