ANECORTAVE아세테이트(200MG)F0E2980.997MG/MG(AI)
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ANECORTAVE아세테이트(200MG)F0E2980.997MG/MG(AI) 속성
- 녹는점
- 230-234°C
- 알파
- D +117° (c = 1.0 in CHCl3); D22 +124° (c = 1.04 in CHCl3).
- 끓는 점
- 551.8±50.0 °C(Predicted)
- 밀도
- 1.23±0.1 g/cm3(Predicted)
- 저장 조건
- -20°C Freezer
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 12.47±0.60(Predicted)
- 색상
- 미색부터 베이지까지
안전
ANECORTAVE아세테이트(200MG)F0E2980.997MG/MG(AI) C화학적 특성, 용도, 생산
개요
Anecortave acetate, an angiogenesis inhibitor, was launched in Australia by Alcon for the treatment of age-related macular degeneration (AMD). AMD is the leading cause of untreatable blindness among people aged 65 to 74 years in the U.S. Worldwide, approximately 20 to 25 million people suffer from AMD, a disease that until recently was untreatable. Anecortave, an angiostatic steroid, down-regulates the expression MMP-2 and -9 to exert its antiangiogenic effects.화학적 성질
Off-White Solid용도
As an angiostatic steroid, Anecortave Acetate can be used in treatment of macular degeneration.효소 저해제
This novel angiogenesis pro-drug (FW = 386.48 g/mol; CAS 7753-60-8) is taken up and metabolically de-esterified to form the aqnecortave, a synthetic steroid that suppresses the development and elongation of neovascular sprouts and tip cell motility in a VEGF-treated retinal explant model in a dose-dependent manner. Whether used as monotherapy or in combination with sub-therapeutic doses of cisplatin, anecortave acetate significantly controlled tumor burden in a murine retinoblastoma model.ANECORTAVE아세테이트(200MG)F0E2980.997MG/MG(AI) 준비 용품 및 원자재
원자재
준비 용품
ANECORTAVE아세테이트(200MG)F0E2980.997MG/MG(AI) 공급 업체
글로벌( 132)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 |
peter@yan-xi.com | China | 6011 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 973 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 16209 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21673 | 55 |
| Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 |
sales@czwytech.com | CHINA | 906 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 |
| Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 +86-15850508050 |
sean.lv@synzest.com | China | 323 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 |
CHINA | 2783 | 58 | |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30253 | 58 |