2,5-다이하이드록시벤조익애씨드
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2,5-다이하이드록시벤조익애씨드 속성
- 녹는점
- 204-208 °C(lit.)
- 끓는 점
- 237.46°C (rough estimate)
- 밀도
- 1.3725 (rough estimate)
- 굴절률
- 1.6400 (estimate)
- 저장 조건
- Store below +30°C.
- 용해도
- 알코올과 에테르에 용해됩니다.
- 산도 계수 (pKa)
- 2.97(at 25℃)
- 물리적 상태
- 결정성 분말
- 색상
- 흰색~밝은 베이지
- 수소이온지수(pH)
- 3.21(1 mM solution);2.56(10 mM solution);2.01(100 mM solution)
- 수용성
- 녹는
- Merck
- 14,4398
- BRN
- 2209119
- InChIKey
- WXTMDXOMEHJXQO-UHFFFAOYSA-N
- LogP
- 1.740
- CAS 데이터베이스
- 490-79-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36/37/38 | ||
안전지침서 | 26-36-37/39 | ||
WGK 독일 | 3 | ||
RTECS 번호 | LY3850000 | ||
위험 참고 사항 | Harmful | ||
TSCA | Yes | ||
HS 번호 | 29182990 |
2,5-다이하이드록시벤조익애씨드 C화학적 특성, 용도, 생산
개요
Gentisic acid is a dihydroxy benzoic acid. It is a derivative of benzoic acid and a minor (1 %) product of the metabolic break down of aspirin, excreted by the kidneys.It is also found in the African tree Alchornea cordifolia and in wine.
화학적 성질
White to light beige crystalline powder. 2,5-Dihydroxybenzoic Acid [490-79-9] (gentisic acid, 2,5-DHBA), C7H6O4, Mr 154.1, mp 205 C, is soluble in water and alcohols but insoluble in benzene and chloroform. The acid is stable in boiling water and gives a deep blue color with iron(III) chloride. Here, the acid decomposes to form p-benzoquinone [106-51-4] and carbon dioxide. 2–5-Dihydroxybenzoic acid is used as an antirheumatic drug and, more recently, as a color developer for thermal paper.용도
2,5-dihydroxybenzoic acid are?used as intermediates for pharmaceuticals (especially for antipyetic anlgesic, antirheumatism) and other organic synthesis. They are used as matrix for ionization of peptides, proteins and carbohydrates. In industrial field, they are?used as intermediates for the production of other organic chemicals, resins, polyesters, plasticizers, dyestuffs, preservatives, and rubber chemicals.주요 응용
As a hydroquinone , gentisic acid is readily oxidized and is used as an antioxidant excipient in some pharmaceutical preparations. In the laboratory, it is used as a sample matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry , and has been shown to conveniently detect peptides incorporating the boronic acid moiety by MALDI .정의
ChEBI: A dihydroxybenzoic acid having the two hydroxy groups at the 2- and 5-positions.생산 방법
Gentisic acid is produced by carboxylation of hydroquinone.C6H4(OH)2 + CO2 → C6H3(CO2H)(OH)2
This conversion is an example of a Kolbe–Schmitt reaction.
일반 설명
Aspirin metabolite.Safety Profile
Poison bp intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.Purification Methods
Crystallise gentisic acid from hot water or *benzene/acetone. Dry it in a vacuum desiccator over silica gel. [Beilstein 10 H 384, 10 IV 1441.]2,5-다이하이드록시벤조익애씨드 준비 용품 및 원자재
원자재
준비 용품
2,5-다이하이드록시벤조익애씨드 공급 업체
글로벌( 559)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12495 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5895 | 58 |
Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 |
sales06@hbduling.cn | China | 8054 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
Sigma Audley | +86-15937194204 +86-18126314766 |
nova@sh-teruiop.com | China | 491 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21663 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9284 | 55 |