피마게딘

피마게딘
피마게딘 구조식 이미지
카스 번호:
79-17-4
한글명:
피마게딘
동의어(한글):
피마게딘
상품명:
pimagedine
동의어(영문):
Aids030897;pimagedine;Aids-030897;Aminate base;1-Aminoguanidine;N-Aminoguanidine;Monoaminoguanidine;Aminoguanidine (ag);Ribavirin Impurity S;Aminoguanidine mordant
CBNumber:
CB5875700
분자식:
CH6N4
포뮬러 무게:
74.09
MOL 파일:
79-17-4.mol

피마게딘 속성

녹는점
182-185 °C (decomp)
끓는 점
159.5±23.0 °C(Predicted)
밀도
1.72±0.1 g/cm3(Predicted)
굴절률
1.6660 (estimate)
산도 계수 (pKa)
11.08±0.70(Predicted)

안전

피마게딘 C화학적 특성, 용도, 생산

용도

Inhibitor (advanced glycosylation end-product formation).

정의

ChEBI: Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.

효소 저해제

This substituted hydrazine (FWhydrochloride = 110.55 g/mol; CAS 79-17-4), also named pimagedine, is a strong inhibitor of diamine oxidases as well as nitric oxide synthase. Note that aminoguanidine also inhibits the formation of advanced glycosylation end-products, reportedly by reacting with and trapping Amadori rearrangement-derived fragmentation products in solution. In view of this property, aminoguanidine has often been used to treat complications associated with chronic diabetes. Target(s): amine oxidase (copper-containing), or diamine oxidase; methylamine dehydrogenase; tryptophan tryptophylquinone enzymes; nitric-oxide synthase; b-fructofuranosidase, or invertase; monoamine oxidase, or amine oxidase; histidine decarboxylase; aldose reductase; catalase; formation of advanced glycosylation end products; adenosylmethionine decarboxylase; arginine deaminase; arginine kinase; aspartate aminotransferase; histamine N-methyltransferase.

피마게딘 준비 용품 및 원자재

원자재

준비 용품


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