클로르나프아진 C화학적 특성, 용도, 생산
화학적 성질
Chlornaphazine is composed of clear, colorless plates or may be a brown solid.
World Health Organization (WHO)
The World Health Organization has no information further to the
above regarding preparations containing chlornaphazine or to indicate that they
are still commercially manufactured.
일반 설명
Colorless plates or brown solid.
공기와 물의 반응
Insoluble in water.
반응 프로필
chlornaphazine reacts with nucleophiles .
화재위험
Flash point data are not available for chlornaphazine , but chlornaphazine is probably combustible.
Safety Profile
Confirmed human carcinogenproducing bladder tumors. Human and experimentalcarcinogenic data. Moderately toxic by intraperitonealroute. When heated to decomposition it emits very toxicfumes of Cl- and NOx.
잠재적 노출
May be combustible and possibly
explosive. Not produced or used commercially in the
United States, Chlornaphazine has been used in other countries in the treatment of leukemia and related cancers.
Currently, this drug does not have wide therapeutic usage.
운송 방법
UN2810 Toxic liquids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name
Required. UN2588 Pesticides, solid, toxic, Hazard Class: 6.1;
Labels: 6.1-Poisonous materials, Technical Name Required.
Purification Methods
Crystallise it from pet ether. At 15o it is soluble in EtOH (3.2%), Et2O (50%), Me2CO (84%) and *C6H6 (80%). [Beilstein 12 III 2996, 12 IV 3126.] CARCINOGENIC.
비 호환성
Keep away from oxidizers, nucleophiles,
and nitromethanes. Amines may react violently with nitric
acid; cellulose nitrate (of high surface area); 1-chloro-2,3-epoxypropane (exothermic reaction may occur). Incompatible with
acids, acid halides; alcohols, aldehydes, alkylene oxides; anhydrides, cresols, caprolactam solution; epichlorohydrin, epoxides, isocyanates, glycols, peroxides, phenols. Contact with
strong reducing agents may generate flammable hydrogen gas.
May attack copper and copper alloys.
폐기물 처리
Disposal of unused product
must be undertaken by qualified personnel who are knowledgeable in all applicable regulations and follow all pertinent safety precautions including the use of appropriate
protective equipment. For proper handling and disposal,
always comply with federal, state, and local regulations.
클로르나프아진 준비 용품 및 원자재
원자재
준비 용품
