aa149;supacal;colibil;TREPIBUTONE;Colibil, Supacal;Trepibutone USP/EP/BP;Trepibutone, 10 mM in DMSO;3-(2,4,5-triethoxybenzoyl)propionicacid;3-(2,4,5-triethoxybenzoyl)-propionicaci;2,4,5-Triethoxy-γ-oxobenzenebutanoic acid
눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P330
입을 씻어내시오.
P332+P313
피부 자극이 생기면 의학적인 조치· 조언을 구하시오.
P337+P313
눈에 대한 자극이 지속되면 의학적인 조치· 조언를 구하시오.
P362
오염된 의복을 벗고 세척 후에 재사용하기
P403+P233
용기는 환기가 잘 되는 곳에 단단히 밀폐하여 저장하시오.
P405
밀봉하여 저장하시오.
P501
...에 내용물 / 용기를 폐기 하시오.
Trepibutone C화학적 특성, 용도, 생산
Originator
Supacal,Takeda,Japan,1981
Manufacturing Process
To a mixture of 7.5 parts by weight of 1,2,4-triethoxybenzene, 40 parts by
volume of tetrachloroethane and 7.5 parts by weight of succinic anhydride are
added 23 parts by weight of anhydrous aluminum chloride. The mixture is
stirred for 1 hour at 25°C and for another 2 hours at 60°C. After addition of
50 parts by weight of ice and 50 parts by volume of concentrated hydrochloric
acid, the reaction mixture is subjected to steam distillation.
After cooling crystals separated from the remaining liquid are collected by
filtration and recrystallized from aqueous ethanol, whereby 2.5 parts by
weight of 3-(2',4',5'-triethoxybenzoyl)-propionic acid are obtained as colorless
needles, melting point 150°C to 151°C.
