팔라시딘

팔라시딘
팔라시딘 구조식 이미지
카스 번호:
26645-35-2
한글명:
팔라시딘
동의어(한글):
팔라시딘
상품명:
PHALLACIDIN
동의어(영문):
PHALLICIDIN;PHALLACIDIN;Phallacidin DISCONTINUED;CYCLO(ALA-2-MERCAPTO-TRP-4;phallacidin from amanita phalloides;Cyclo(Ala-2-Mercapto-Trp-4;5-DIHYDROXY-LEU-VAL-ERYTHRO-3-HYDROXY-D-ASP-CYS-CIS-4-HYDROXY-PRO);-3-hydroxy-d-alpha-aspartyl-l-cysteinyl-cis-4-hydroxy-l-prolyl)cyclic(2-6)-s;cyclic(l-alanyl-2-mercapto-l-tryptophyl-4,5-dihydroxy-l-leucyl-l-valyl-erythro;Cyclo[L-Ala-L-Trp2(1)-4,5-dihydroxy-L-Leu-L-Val-[(3S)-3-hydroxy-D-Asp-]-L-Cys(1)-L-c4Hyp-]
CBNumber:
CB6136097
분자식:
C37H50N8O13S
포뮬러 무게:
846.9
MOL 파일:
26645-35-2.mol

팔라시딘 속성

밀도
1.1678 (rough estimate)
굴절률
1.7400 (estimate)
용해도
DMF: Soluble; DMSO: Soluble; Methanol: Soluble; Water: Soluble
물리적 상태
백색 내지 회백색 분말.
안전
  • 위험 및 안전 성명
위험품 표기 T+
위험 카페고리 넘버 26/27/28
안전지침서 22-36/37/39-45
유엔번호(UN No.) 1544
WGK 독일 3
RTECS 번호 GT8943000
위험 등급 6.1(a)
포장분류 I
HS 번호 2934999090
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P262 눈, 피부, 의복에 묻지 않도록 하시오.
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
NFPA 704
0
4 0

팔라시딘 C화학적 특성, 용도, 생산

개요

Phallacidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. It binds filamentous actin (F-actin) like phalloidin , but contains a carboxyl group for coupling reactions.

용도

Toxin Phallacidin is a weak fluorescent bicyclic peptide probe in aquous solution, Which is isolated from Amanita phalloides mushroom and could be used for blocking F-actin staining by labeled phallotoxins, which promotes actin polymerization.

정의

ChEBI: A homodetic bicyclic heptapeptide having a sulfide bridge.

효소 저해제

This cyclic heptapeptide toxin (FWfree-acid = 846.92 g/mol; CAS 26645-35-2) from the poisonous green fungus Amanita phalloides stabilizes actin filaments and inhibits actin filament depolymerization. NBD phallacidin is a high-affinity, filamentous actin probe consisting of rabbit actin that is conjugated by reacting its thiol group with 4-chloro-7- nitrobenzofurazan, a yellow-green fluorescent dye. NBD phallacidin (Excitation at 465 nm; Emission at 536 nm) selectively stains F-actin un a manner that is superior to antibody staining, preferably in fixed and permeabilized samples. See Phalloidin

팔라시딘 준비 용품 및 원자재

원자재

준비 용품


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