ChemicalBook >제품 카탈로그 >1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린

1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린

1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린 구조식 이미지

카스 번호:: 112037-78-2

한글명:: 1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린

동의어(한글):: 1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린

상품명:: 1-TRIFLUOROMETHYL-2,3,4,9-TETRAHYDRO-1H-B-CARBOLINE

동의어(영문):: -carboline;3-Methyl αNorharmane (9H-Pyrido[3,4-b]indole, ß1,2,3,4-Tetrahydro-1-(trifluoromethyl)-ßrac 1-Trichloromethyl-1,2,3,4-Tetrahydro-β(S)-1-Trichloromethyl-1,2,3,4-Tetrahydro-β1,2,3,4-Tetrahydro-1-(trifluoroMethyl)--carboline;1-TRIFLUOROMETHYL-2,3,4,9-TETRAHYDRO-1H-B-CARBOLINE;1,2,3,4-TETRAHYDRO-1-(TRIFLUOROMETHYL)-BETA-CARBOLINE;1-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-beta-carboline

CBNumber:: CB6140573

분자식:: C12H11F3N2

포뮬러 무게:: 240.22

MOL 파일:: 112037-78-2.mol

속성

안전

용도

공급 업체 13

1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린 속성

녹는점: 147-149°C

끓는 점: 350.0±37.0 °C(Predicted)

밀도: 1.351±0.06 g/cm3(Predicted)

산도 계수 (pKa): 16.63±0.40(Predicted)

안전

위험 카페고리 넘버	36/37/38
안전지침서	26-36/37/39

1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린 C화학적 특성, 용도, 생산

Mechanism of action

Although βCCE and other β-carbolines are not endogenous BZR ligands (vide supra) and are not currently approved for clinical use, they are used to characterize different GABAA/BZR subtypes (based on a and g subunit composition) and function (e.g., the partial agonist abecarnil) toward the discovery of anxioselective drugs. In this regard, the β-carboline ring system is planar in comparison to the boat conformation of the 1,4-benzodiazepines; thus, β-carbolines have been useful to extend structure–activity relationship information for the agonist, antagonist, and inverse agonist pharmacophores of the various GABAA/BZR subtypes.

Clinical Use

Several β-carbolines have approximately 10-fold higher affinity for the BZR when compared to diazepam. The ethyl ester of β-carboline-3-carboxylic acid (βCCE), identified in human urine extracts as an artifact of the extraction procedure, has very high affinity for the BZR.

1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린 준비 용품 및 원자재

원자재

TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL 트립타민

준비 용품

1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린 공급 업체

글로벌( 13)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30253	58
Hangzhou Yuhao Chemical Technology Co., Ltd	0571-82693216	info@yuhaochemical.com	China	9394	52
United States Biological	--	sales@advtechind.com	United States	6106	58

1-트리플루오로메틸-2,3,4,9-테트라히드로-1H-B-카르볼린 관련 검색:

N-(4-CHLORO-3-NITROPHENYL)-1-(TRIFLUOROMETHYL)-1,3,4,9-TETRAHYDRO-2H-BETA-CARBOLINE-, TECH 2,3,3-TRICHLORO-1-[1-(TRIFLUOROMETHYL)-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLIN-2-YL]PROP-2-EN-1-ONE 1-(P-CHLOROBENZYL)-2,3,4,9-TETRAHYDRO-1-(TRIFLUOROMETHYL)-1H-B-CARBOLINE N-(4-CHLORO-3-NITROPHENYL)-1-(TRIFLUOROMETHYL)-1,3,4,9-TETRAHYDRO-2H-BETA-CARBOLINE-2-CARBOXAMIDE 1-TRIFLUOROMETHYL-2,3,4,9-TETRAHYDRO-1H-B-CARBOLINE 2-CHLORO-1-[1-(TRIFLUOROMETHYL)-1,3,4,9-TETRAHYDRO-2H-BETA-CARBOLIN-2-YL]ETHAN-1-ONE 2,3,4,9-TETRAHYDRO-1-(P-NITROBENZYL)-1-(TRIFLUOROMETHYL)-1H-B-CARBOLINE