2-메틸이미다졸
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2-메틸이미다졸 속성
- 녹는점
- 142-143 °C (lit.)
- 끓는 점
- 267-268 °C (lit.)
- 밀도
- 1.0500 (rough estimate)
- 증기압
- <1 mm Hg ( 0 °C)
- 굴절률
- 1.4970 (estimate)
- 인화점
- 155 °C
- 저장 조건
- 2-8°C
- 용해도
- 780g/L
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 14.44±0.10(Predicted)
- 색상
- 흰색에서 밝은 노란색
- 수소이온지수(pH)
- 10.5-11.5 (100g/l, H2O, 20℃)
- pH 범위
- 10.5
- 수용성
- 물과 에탄올에 용해됩니다.
- BRN
- 1368
- InChIKey
- LXBGSDVWAMZHDD-UHFFFAOYSA-N
- LogP
- 0.22 at 25℃
- CAS 데이터베이스
- 693-98-1(CAS DataBase Reference)
- IARC
- 2B (Vol. 101) 2013
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | C | ||
---|---|---|---|
위험 카페고리 넘버 | 22-34 | ||
안전지침서 | 26-36/37/39-45-25 | ||
유엔번호(UN No.) | UN 3259 8/PG 2 | ||
WGK 독일 | 2 | ||
RTECS 번호 | NI7175000 | ||
자연 발화 온도 | >600 °C DIN 51794 | ||
위험 참고 사항 | Harmful/Corrosive | ||
TSCA | Yes | ||
위험 등급 | 8 | ||
포장분류 | III | ||
HS 번호 | 29332990 | ||
유해 물질 데이터 | 693-98-1(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: 1500 mg/kg | ||
기존화학 물질 | KE-24299 |
2-메틸이미다졸 C화학적 특성, 용도, 생산
용도
2-Methylimidazole는 생물학으로 활동적인 화합물의 광범위의 준비에 있는 빌딩 블록으로 이용될 수 있는 monomethylated 이미다졸입니다. 2-Methylimidazole 뿐 아니라 다른 이미다졸은 강화한 착색한 형광성 단백질의 refolding를 위한 촉매 사용일 수 있습니다. 2-Methylimidazole는 발효작용의 부산물로 확인되고 음식 및 주류 및 측 str eam 담배 연기에서 검출됩니다.화학적 성질
2-Methylimidazole is a white to light yellow crystalline powder with an amine-like odor. It is highly soluble in polar organic solvents. Insoluble in ether and cold benzene, easily soluble in water, alcohols and ketones. Irritating to skin and mucous membranes. Mice orally LD50 1400mg/kg.화학적 성질
The 2-methylimidazole molecule is approximately planar, and the maximum deviation of all non-H atoms from the plane of the least squares imidazole is 0.006(2)?. N–H··· N hydrogen bonds link molecules together to form infinite chains of hydrogen bond pattern C(4). The crystal of 2-methylimidazole is in orthorhombic crystal system with space group P212121 (Z = 4), lattice parameters: a = 5.9957(12) ?, b = 8.1574(16) ? and c = 9.7010(19) ?, V = 474.47(16) ?[1].용도
2-Methylimidazole is a monomethylated imidazole that can be used as a building block in the preparation of a wide range of biologically active compounds. 2-Methylimidazole as well as other imidazoles can be use as catalyst for refolding of enhanced coloured fluorescent protein. 2-Methylimidazole has been identified as a byproduct of fermentation and is detected in foods and mainstream and side-str eam tobacco smoke.일반 설명
It is a white or colorless solid that is highly soluble in polar organic solvents and water. It is a precursor to a range of drugs and is a ligand in coordination chemistry.위험도
Possible carcinogen.Purification Methods
Recrystallise 2-methylimidazole from *benzene or pet ether. The picrate has m 215o (from H2O). [Beilstein 23 III/IV 594, 23/5 V 35.]참고 문헌
[1] Hachu?a B, et al. Crystal and Molecular Structure Analysis of 2-Methylimidazole. Journal of Chemical Crystallography, 2009; 40: 201–206.2-메틸이미다졸 준비 용품 및 원자재
원자재
2-메틸-2-이미다졸린
글리옥살
아세토나이트릴
에틸렌디아민
아세트알데히드
암모니아(가스)
1,8-다이아미노옥테인
이미다졸-2-카르복스알데히드
1,12-도데칸디아민
2-메틸-4(5)-아이오도-1(H)-이미다졸
준비 용품
2-메틸이미다졸 공급 업체
글로벌( 847)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 |
info@allgreenchem.com | China | 5986 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12450 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
daisy@crovellbio.com | China | 5828 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 |
sales1@hbganmiao.com | China | 253 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 |
lisa@kingfinertech.com | China | 2989 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 10977 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20294 | 58 |
Wuhan Ruichi Technology Co., Ltd | +8613545065237 |
admin@whrchem.com | China | 161 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 |
sales06@airuikechemical.com | China | 983 | 58 |
2-메틸이미다졸 관련 검색:
1,3-디메틸-2-이미다졸리디논 1,2-다이메틸이미다졸 플루싸이트린에이트 2-에틸l-4-메틸이미다졸 1-메틸이미다졸
Methyl 1-methylimidazole-5-carboxylate 97%
4-Ethoxycarbonyl-5-methylimidazole
5-Chloro-1-methylimidazole,98%
1-Butyl-3-methylimidazolium chloride
5-Methylimidazole-4-carboxaldehyde,99%
4-Methylimidazole
2-Chloromethylimidazoline
1-Butyl-3-methylimidazolium trifluoromethansulfonate
1-butyl-3-methylimidazolium chloride
3-fluoro-4-(4-methylimidazole)benzenamine
Benzoylmetronildazole
1,1'-CARBONYLBIS(2-METHYLIMIDAZOLE)
5-[(TRIMETHYLSILYL)]-1-METHYLIMIDAZOLE