눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
1
2
0
2-Amino-5-bromopyrimidine C화학적 특성, 용도, 생산
화학적 성질
Yellow Solid
용도
2-Amino-5-bromopyrimidine was employed:
in synthesis of pyridine, pyrimidine and pyridinone C-nucleoside phosphoramidites
in synthesis of 2-phthalimido-5-bromopyrimidine
as intermediate for the preparation of sulfanilamides and amino acids containing the pyrimidine ring system. The products are potential antiviral agents
일반 설명
Crystal structure of 2-amino-5-bromopyrimidine was studied.
Synthesis
The synthesis of 2-Amino-5-bromopyrimidine is as follows:The 2-aminopyrimidine (2.5g, 26.29mmol) was dissolved in acetonitrile (25mL) was added N- bromosuccinimide (4.6g, 27.9mmol) under ice-cooling, stirred in the dark overnight at room temperature. Recovery of the solvent under reduced pressure, washed with water (100 mL) was washed, filtered off with suction, and dried in vacuo to give a white solid. Yield: 97%.
저장
Store in cool, well ventilated area. Keep container tightly closed. Light sensitive. Store under argon.
