크산티드롤
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크산티드롤 속성
- 녹는점
- 122-124 °C
- 끓는 점
- 275.53°C (rough estimate)
- 밀도
- 0.83 g/mL at 20 °C
- 굴절률
- 1.6620 (estimate)
- 인화점
- 11 °C
- 저장 조건
- 2-8°C
- 용해도
- 메탄올: 0.1 g/mL, 투명
- 산도 계수 (pKa)
- 13.57±0.20(Predicted)
- 물리적 상태
- 결정성 분말
- 색상
- 흰색에서 황백색까지
- 감도
- Light Sensitive
- BRN
- 10395
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
- LogP
- 2.270 (est)
- CAS 데이터베이스
- 90-46-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F,T,Xi,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 11-23/24/25-39/23/24/25-40 | ||
안전지침서 | 7-16-24-45-24/25-36-22-36/37 | ||
유엔번호(UN No.) | UN 1230 3/PG 2 | ||
WGK 독일 | 3 | ||
RTECS 번호 | ZD5710000 | ||
F 고인화성물질 | 8-10-23 | ||
위험 참고 사항 | Irritant | ||
TSCA | Yes | ||
HS 번호 | 29329990 |
크산티드롤 C화학적 특성, 용도, 생산
화학적 성질
White needle crystals. Melting point 123℃, easily soluble in cold acetone, soluble in alcohol, chloroform, very slightly soluble in water. Dissolved in concentrated sulfuric acid, it is yellow and has green fluorescence.용도
9-Hydroxyxanthene is an Intermediate in the preparation of Propantheline Bromide. It is useful in tests for urea also used in the protection of thiols as their S-xanthenyl (Xan) thioethers, by reaction in the presence of TFA.주요 응용
Xanthydrol may be used as a derivatization agent for the following:Analysis of urea in urine and wine samples using high-performance liquid chromatography (HPLC) technique.
Analysis of trace levels of carbamate pesticides in surface water by gas chromatography–mass spectrometry (GC-MS).
정의
9H-Xanthen-9-ol is a derivative of xanthene that is a natural product found in Xanthium spinosum and Xanthium strumarium.제조 방법
synthesis of xanthydrol: The amalgam sodium in dry toluene was warmed to 50°C, the xanthone-ethanol suspension was added, and the temperature was rapidly raised to 60-70°C with vigorous stirring. After the reaction is completed, the mercury is separated. The reaction solution was filtered, the filtrate was poured into the stirred blue distilled water, the 9-hydroxyxanthene was filtered out, washed with water, and dried to obtain the finished product with a yield of 91-95%.화학 반응
9-Hydroxyxanthene (xanthydrol) reacts with a variety of proteins and inactivates certain enzymes. The research data indicate that in acetic acid solution xanthydrol reacts with the following amino acids: arginine, asparagine, cysteine, glutamine, histidine, lysine, and tryptophan. The a-amino group of cu-amino acids does not react with xanthydrol under these conditions, since alanine, serine, isoleucinc, and tyrosine failed to react[1]. This compound could help to increase extraction efficiency, because it could react with ethyl carbamate to form low-polar product, which facilitated transfer ethyl carbamate into organic phase[2].일반 설명
Xanthydrol is also known as 9H-xanthen-9-ol. Xanthydrol is a natural drug that has been used in traditional Chinese medicine for treating a variety of diseases. It is extracted from Rhizoma Gastrodiae and Angelicae Dahuricae. It has shown to be effective against various metabolic disorders, including insulin resistance, hyperlipidemia, and diabetes. The mechanism of action of Xanthydrol is not known but it is thought to be due to its ability to activate the immune system by transferring reactions and promoting the production of antibodies. It also shows anti-inflammatory effects by inhibiting the production of prostaglandins and leukotrienes. It can also inhibit angiotensin II, which may reduce high blood pressure and congestive heart failure.Purification Methods
Crystallise xanthydrol from EtOH and dry it at 40-50o. [Beilstein 17 H 129, 17 I 72, 17 II 146, 17 III/IV 1602, 17/4 V 502.]크산티드롤 준비 용품 및 원자재
원자재
Amalgam sodium
크산톤
NSC26684
2-(2-bromophenoxy)benzaldehyde
페놀
9,9- 디메틸 -4,5- 비스 (디 페닐 포스 피노) 크 산텐
2-클로로벤조익산
준비 용품
크산티드롤 공급 업체
글로벌( 199)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shanghai Gubang New Materail Technology Co. LTD | 21-51317962 +8618721305404 |
16728589@qq.com | CHINA | 272 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9284 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 |
sales@ansciepchem.com | CHINA | 4242 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8820 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 |
info@longyupharma.com | China | 2534 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29821 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 13392 | 58 |