VU0483605

VU0483605 구조식 이미지
카스 번호:
1623101-11-0
상품명:
VU0483605
동의어(영문):
VU0483605;3-Chloro-N-(3-chloro-4-(4-chloro-1,3-dioxoisoindolin-2-yl)phenyl)picolinamide;3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide;2-Chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)phenyl]nicotinamide;3-Chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide;3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]pyridine-2-carboxamide;2-Pyridinecarboxamide, 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-;Inhibitor,inhibit,VU0483605,Metabotropic glutamate receptors,allosteric modulator,brain penetrant,metabotropic glutamate,VU 0483605,mGluR,VU-0483605
CBNumber:
CB63067594
분자식:
C20H10Cl3N3O3
포뮬러 무게:
446.67
MOL 파일:
1623101-11-0.mol

VU0483605 속성

밀도
1.625±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
≤20mg/ml in DMSO;20mg/ml in dimethyl formamide
물리적 상태
결정질 고체
산도 계수 (pKa)
9.39±0.70(Predicted)
색상
Light yellow to orange

안전

VU0483605 C화학적 특성, 용도, 생산

용도

VU 0483605 is a positive allosteric modulator of metabotropic glutamate receptors (mGluRs) that preferentially binds mGlu1 over mGlu4 (1,2). VU 0483605 is a mGlu1 antagonist and has potential therapeutic properties for treating schizophrenia.

VU0483605 준비 용품 및 원자재

원자재

준비 용품


VU0483605 공급 업체

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