GQ-16

GQ-16 구조식 이미지
카스 번호:
870554-67-9
상품명:
GQ-16
동의어(영문):
GQ-16;GQ-16 Exclusive;5Z-[(5-bromo-2-methoxyphenyl)methylene]-3-[(4-methylphenyl)methyl]-2,4-thiazolidinedione;2,4-Thiazolidinedione, 5-[(5-bromo-2-methoxyphenyl)methylene]-3-[(4-methylphenyl)methyl]-, (5Z)-;(5Z)-5-[(5-bromo-2-methoxyphenyl)methylidene]-3-[(4-methylphenyl)methyl]-1,3-thiazolidine-2,4-dione;PPAR,Inhibitor,reduced adipogenic actions,PPARγ,GQ-16,insulin sensitization,inhibit,Peroxisome proliferator-activated receptors,insulin Resistance,GQ16,GQ 16
CBNumber:
CB63152621
분자식:
C19H16BrNO3S
포뮬러 무게:
418.3
MOL 파일:
870554-67-9.mol

GQ-16 속성

녹는점
147 °C
끓는 점
549.8±60.0 °C(Predicted)
밀도
1.522±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
≤0.33mg/ml in DMSO;5mg/ml in dimethyl formamide
물리적 상태
결정질 고체
산도 계수 (pKa)
-2.57±0.20(Predicted)
색상
Off-white to light yellow

안전

GQ-16 C화학적 특성, 용도, 생산

개요

Full activation of peroxisome proliferator-activated receptor γ (PPARγ), e.g., using thiazolidinediones, effectively treats insulin resistance and type 2 diabetes but also commonly promotes weight gain, hyperphagia, and edema. GQ-16 is a partial agonist for PPARγ (Ki = 160 nM) which induces adipogenesis significantly less than the full activator rosiglitazone. Like rosiglitazone, GQ-16 reverses high fat diet-mediated impairments in insulin signaling. However, GQ-16 does not induce weight gain, hyperphagia, or edema. GQ-16 does not activate PPARα, PPARβ/δ, or RXRα.

GQ-16 준비 용품 및 원자재

원자재

준비 용품


GQ-16 공급 업체

글로벌( 39)공급 업체
공급자 전화 이메일 국가 제품 수 이점
LEAPCHEM CO., LTD.
+86-852-30606658
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BOC Sciences 16314854226
info@bocsci.com United States 9926 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123
1014988033@qq.com China 4930 55
Yujinpharma(Tianjin) Technology Co.,Ltd. 13370351217 kungfu1217@1
kungfu1217@163.com China 9124 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8141 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761
486064515@qq.com China 3336 58
Bide Pharmatech Ltd. 400-1647117 13681763483
product02@bidepharm.com China 62163 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24647 58

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