(R)-N-Boc-3-피롤리딘아세트산
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(R)-N-Boc-3-피롤리딘아세트산 속성
- 끓는 점
- 357.4±15.0 °C(Predicted)
- 밀도
- 1.151±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 산도 계수 (pKa)
- 4.65±0.10(Predicted)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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| 유해·위험 문구: |
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| 예방조치문구: |
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(R)-N-Boc-3-피롤리딘아세트산 C화학적 특성, 용도, 생산
Synthesis
(R)-N-Boc-3-pyrrolidineacetic acid is synthesised using Di-tert-butyl dicarbonate as raw material by chemical reaction. The specific synthesis steps are as follows:A solution of 4.95 g of the preceding step product in 50 ml of dichloromethane and 25 ml of trifluoroacetic acid is stirred at room temperature for 3 h. and concentrated. The residue is dissolved in 40 ml of dioxan and 40 ml of 1N NaOH, treated at room temperature with 4.3 g of di-tert-butyl dicarbonate in 40 ml of dioxan and stirred for 1.5 h. The reaction mixture is diluted with ether, the organic phase is washed with 1N NaOH and the aqueous phase is acidified with 3N HCl. Extraction of the aqueous phase with ether, washing, drying and concentration of the ether phase gives 0.72 g of tert-butyl(R)-3-carboxymethyl-pyrrolidine-1-carboxylate.
(R)-N-Boc-3-피롤리딘아세트산 준비 용품 및 원자재
원자재
(R)-diethyl 2-(1-(tert-butoxycarbonyl)pyrrolidin-3-yl)malonate
tert-Butyl (3S)-3-({[(4-methylbenzene)sulfonyl]oxy}methyl)pyrrolidine-1-carboxylate
(R)-2-(1-(tert-butoxycarbonyl)pyrrolidin-3-yl)Malonic acid
(S)-3-시아노메틸-피롤리딘-1-카르복실산TERT-부틸에스테르
(S)-3-하이드록시메틸-피롤리딘-1-카복실산tert-부틸에스테르
(R)-3-하이드록시메틸-피롤리딘-1-카복실산tert-부틸에스테르
에틸2-클로로-4-에톡시-니코티네이트
디 -Tert- 부틸 디 카보네이트
준비 용품
(R)-N-Boc-3-피롤리딘아세트산 공급 업체
글로벌( 124)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29791 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 810 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 |
info@accelachem.com | United States | 17159 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 |
info@edengenechem.com | China | 2158 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29814 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 |
joe@yuhengpharm.com | CHINA | 21142 | 58 |