Cdk1/2 Inhibitor III
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Cdk1/2 Inhibitor III 속성
- 끓는 점
- 649.1±65.0 °C(Predicted)
- 밀도
- 1.72±0.1 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- ≤10mg/ml in DMSO
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 6.61±0.70(Predicted)
- 색상
- White to off-white
안전
Cdk1/2 Inhibitor III C화학적 특성, 용도, 생산
개요
Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/2 Inhibitor III is a cell-permeable inhibitor of Cdk1/cyclin B and Cdk2/cyclin A (IC50s = 0.6 and 0.5 nM, respectively). It less potently inhibits CDC2-like kinases 1 and 3, VEGFR2, and GSK-3β (IC50s = 8.9, 29, 32, and 140 nM, respectively) and is without effect against a panel of other kinases. Cdk1/2 Inhibitor III blocks the growth of several cancer cell lines (IC50 values range from 20 to 92 nM).용도
Cdk1/2 Inhibitor III is a cyclin-?dependent kinase (CDK) inhibitor. Cdk1 and Cdk2 performs inhibitory activities, and in vitro cellular proliferation in various human tumor cells.Cdk1/2 Inhibitor III 준비 용품 및 원자재
원자재
준비 용품
Cdk1/2 Inhibitor III 공급 업체
글로벌( 11)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| BOC Sciences | 16314854226 |
info@bocsci.com | United States | 9926 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9806 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24647 | 58 |
| RD International Technology Co., Limited | 18024082417 |
market@ubiochem.com | China | 9268 | 58 |
| ApexBio Technology | -- |
sales@apexbt.com | United States | 6254 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 |
cindy.huang@synzest.com | China | 12007 | 58 |