T-2 TOXIN
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T-2 TOXIN 속성
- 녹는점
- 151.5℃
- 알파
- D26 +15° (c = 2.58 in ethanol)
- 끓는 점
- 489.35°C (rough estimate)
- 밀도
- 1.1942 (rough estimate)
- 굴절률
- 1.6230 (estimate)
- 인화점
- 2 °C
- 저장 조건
- −20°C
- 용해도
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 13.24±0.70(Predicted)
- 색상
- 하얀색
- Merck
- 13,9872
- IARC
- 3 (Vol. 31, Sup 7) 1987
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T+,T,Xn,F | ||
---|---|---|---|
위험 카페고리 넘버 | 26/27/28-38-36-20/21/22-11 | ||
안전지침서 | 28-36/37-45-36-26-16-36/37/39-22 | ||
유엔번호(UN No.) | UN 3462 6.1/PG 1 | ||
WGK 독일 | 3 | ||
RTECS 번호 | YD0100000 | ||
F 고인화성물질 | 10-21 | ||
위험 등급 | 6.1(a) | ||
포장분류 | I | ||
HS 번호 | 29329990 | ||
유해 물질 데이터 | 21259-20-1(Hazardous Substances Data) | ||
독성 | LD50 orally in female rats: 4.0 mg/kg (Marasas); LD50 (mg/kg) in mice: 5.2 i.p., 4.2 i.v.; in rats: 7.0 intragastric, 0.9-1.3 i.p., 0.9 i.v., 2.0 s.c.; in guinea pigs: 3.0-4.0 orally, 5.3 intragastric, 1.0 i.m., 1.0-2.0 i.v., 1.0-2.0 s.c.; in pigs: 5.0 orally, 3.0 i.v. (Yagen, Bailer) |
T-2 TOXIN C화학적 특성, 용도, 생산
개요
T-2 toxin is a trichothecene mycotoxin that has been found in Fusarium. It binds to and inhibits peptidyltransferase in the 60S ribosomal subunit, inducing a ribotoxic stress response that triggers JNK and p38 MAPK signaling. T-2 toxin (3 nM) decreases toll-like receptor expression and LPS-induced production of IL-1β, TNF-α, and nitric oxide (NO) in, and is cytotoxic to (IC50 = 19.47), primary pig alveolar macrophages (PAMs). In vivo, T-2 toxin induces production of reactive oxygen species (ROS), lipid peroxidation, and glutathione (GSH) depletion in mouse brain and is lethal to mice (LD50s = 1.54-5.94 mg/kg). It also induces hepatocyte apoptosis and dyslipidemias in mice. T-2 toxin has been found in Fusarium-infected wheat, barley, and rice crops both in fields and in storage.화학적 성질
White powder용도
T-2 Toxin is a tricothecene mycotoxin produced by fungi of the genus Fusarium. T-2 Toxin induces DNA damage and cell death on prolonged administration.일반 설명
T-2 Toxin is found to be a potent trichothecene mycotoxin produced by the genus fusarium fungi in feedstuffs and cereal grains.Safety Profile
Poison by ingestion, intramuscular, subcutaneous, intraperitoneal, intracerebral, and intravenous routes. Moderately toxic by inhalation. Experimental teratogenic and reproductive effects. A skin irritant. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.T-2 TOXIN 준비 용품 및 원자재
원자재
준비 용품
T-2 TOXIN 공급 업체
글로벌( 121)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29825 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |
HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 |
ada@ipurechemical.com | CHINA | 3465 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8474 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33350 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 |
orders@jknbiochem.com | China | 5224 | 58 |
T-2 TOXIN 관련 검색:
제랄레논 테트라하이드로-4-메틸-2-(2-메틸-1-프로페닐)-2H-피란
Toxin HT 2,T-2, Toxin analog
toxin,bluegreenalga,microcystisaeruginos
TRANS-1,4-CYCLOHEXENEDIOL
T-2 TOXIN
DIACETOXYSCIRPENOL
NEOSOLANIOL
deacetyl-ht-2toxi
scirpentriol
T-2 TETRAOL
VERRUCAROL
gb2toxi
entero-toxin(staphylococcusreduced
PERTUSSIS TOXIN BRP
DIPHTHERIA TOXIN BRP - * BIOTOX
1KTX SCORPION TOXIN
SHK TOXIN