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H1152,이염화수소

H1152,이염화수소 구조식 이미지

카스 번호:: 871543-07-6

한글명:: H1152,이염화수소

동의어(한글):: H1152,이염화수소

상품명:: H1152, DIHYDROCHLORIDE

동의어(영문):: H-1152 2HCl;H1152, DIHYDROCHLORIDE;H-1152 2HCl|||H-1152 dihydrochloride;H 1152 DIHYDROCHLORIDE; H1152 DIHYDROCHLORIDE;4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline;5-[[(2S)-Hexahydro-2-Methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-Methylisoquinoline;H1152P2HCl,(S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolynyl)sulfonyl]homopiperazineDihydrochloride;H1152P Dihydrochloride, (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolynyl)sulfonyl]homopiperazine Dihydrochloride

CBNumber:: CB6506731

분자식:: C16H21N3O2S

포뮬러 무게:: 319.42184

MOL 파일:: 871543-07-6.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 51

H1152,이염화수소 속성

녹는점: 182-184°C

저장 조건: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

용해도: 에 용해됨메탄올, 물

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 흰색에서 황백색까지

안정성: 흡습성

안전

H1152,이염화수소 C화학적 특성, 용도, 생산

화학적 성질

White to Off-White Solid

용도

ROCK Inhibitor. A cell-permeable isoquinolinesulfonamide compoud that acts as a highly specific, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase (ROCK: Ki=1.6nM). Exhibits a much weaker affinity for other serine/threonine

일반 설명

A cell-permeable isoquinolinesulfonamide compound that acts as a highly specific, reversible, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase (ROCK; K_i = 1.6 nM). Exhibits a much weaker affinity for other serine/threonine kinases (K_i = 630 nM for PKA, 9.27 μM for PKC, and 10.1 μM for MLCK). Shown to selectively block lysophosphatidic acid-induced, but not PDBu-induced, phosphorylation of myristoylated alanine-rich C kinase substrate MARCKS (IC₅₀ = 2.5 μM) in NT-2 cells. Reported to be more potent and selective than Y-27632 (Cat. Nos. 688000 and 688001). Mainly targets Aurora Kinase A, and induces polyploidization of acute megakaryocytic leukemia cells (AMKL). At 10 mM (500 μg/128 μl) solution of Rho Kinase Inhibitor (Cat. No. 555552) in H₂O is also available.

H1152,이염화수소 준비 용품 및 원자재

원자재

준비 용품

H1152,이염화수소 공급 업체

글로벌( 51)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei Chuchang Biotech Co., Ltd.	+86-18727130788 +86-18727130788	info@chuchangbiotech.com	China	109	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7553	61
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	United States	4863	58
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2784	58
SPIRO PHARMA		eric_feng1954@126.com	China	9254	55