트리메틸포스파이트

트리메틸포스파이트 속성

트리메틸포스파이트 MSDS

Phosphorous acid trimethyl ester

트리메틸포스파이트 C화학적 특성, 용도, 생산

화학적 성질

Trimethyl phosphite is a colorless liquid. Distinctive pungent, pyridine-like odor. The Odor Threshold is 0.0001 ppm.

용도

Trimethyl phosphite has been used primarily as an intermediate in the manufacture of pesticides and the synthesis of organophosphate insecticides. It is also used as a fire retardants in the production of textiles, as an intermediate in the production of flame-retardant polymers for polyurethane foams, and as a catalyst.

정의

ChEBI: Trimethyl phosphite is an organophosphorus compound that is phosphane in which the three hydrogens are replaced by methoxy groups. It is an alkylating agent used primarily in the synthesis of organophosphate compounds. It has a role as an alkylating agent.

생산 방법

Produced via a reaction between phosphorus trichloride and methanol in the presence of a tertiary amine catalyst such as diethylaniline.

일반 설명

Trimethyl phosphite appears as a clear colorless liquid with a strong foul odor. Flash point 99°F. Denser than water and insoluble in water. Vapors heavier than air. It is used in making pesticides, flame retardants and organophosphorous additives.

공기와 물의 반응

Highly flammable. Insoluble in water and denser than water. Slowly reacts with water to form phosphoric acid and corresponding organic alcohol. Trimethyl phosphite hydrolyzes in water to form dimethyl phosphite and methanol. The hydrolysis rate of trimethyl phosphite is expected to be similar to the hydrolysis rate of triethyl phosphite(SRC).

반응 프로필

As soon as Trimethyl phosphite contacted a small amount of magnesium perchlorate in a flask, there was a flash and an explosion that shattered the flask (Allison 1968).

건강위험

Trimethyl phosphite is a skin, eye, and mucous membrane irritant with low subacute inhalation toxicity. Its irritating action on rabbits’ skin was moderate to severe. The pure liquid instilled into the eyes can cause severe irritation and swelling, which can last for a few days. Chronic exposure to 300–600 ppm concentration in air produced lung inflammation and cataracts in mice. There was no acute inhalation toxicity observed in test animals. The oral and dermal toxicities were low.
LD50 value, oral (rats): 1600 mg/kg
Teratogenic effects showing gross abnormalities were observed in newborn rats when pregnant rats were dosed with high concentrations of trimethyl phosphite.
The odor threshold for this compound was determined to be 0.0001 ppm (ACGIH 1986). The odor is irritating and pungent at high concentrations..

화재위험

Special Hazards of Combustion Products: Toxic fumes of PO x

Safety Profile

Moderately toxic by ingestion and skin contact. An experimental teratogen. A severe skin and eye irritant. Flammable liquid when exposed to heat, flame, or oxidizers. To fight fire, use water, foam, fog, CO2. Violent explosive reaction on contact with magnesium perchlorate or trimethyl platinum(IV) azide tetramer. When heated to decomposition it emits toxic fumes of POx. An intermediate in the production of pesticides, fire retardants, and organic phosphorus additives. See also ESTERS.

잠재적 노출

Trimethyl phosphite is a flame retardant, and used as an intermediate in the manufacture of a number of pesticides, and organophosphorus additives.

Carcinogenicity

Trimethyl phosphite was genotoxic in mouse lymphoma assays but was not mutagenic in various bacterial assays.

운송 방법

UN2329 Trimethyl phosphite, Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

Treat the phosphite with Na (to remove water and any dialkyl phosphonate), then decant and distil it with protection against moisture. It has also been treated with sodium wire for 24hours, then distilled in an inert atmosphere onto activated molecular sieves [Connor et al. J Chem Soc, Dalton Trans 511 1986]. It can be fractionally distilled using a spinning band column at high reflux ratio. It is a colourless liquid which is slowly hydrolysed by H2O. [Gillis et al. J Am Chem Soc 80 2999 1958, NMR: Callis et al. J Am Chem Soc 79 2719 1957, Kosolapoff Organophosphorus Compounds, Wiley p 203 1950, Beilstein 1 IV 1256.]

비 호환성

Vaor May form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Violent reaction with magnesium perchlorate. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Reacts (hydrolyzes) with water. Incompatible with air, moisture.

폐기물 처리

Trimethyl phosphite may be burned in a chemical incinerator equipped with an afterburner and scrubber.

트리메틸포스파이트 준비 용품 및 원자재

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트리메틸포스파이트 공급 업체

공급자	전화	이메일	국가	제품 수	이점
JINAN QUANSHENG CHEMICAL CO.,LTD	0531-80962058 13012986817	961556194@qq.com	China	96	58
shanghaidelaikekejiyouxiangongsi	17351445187	3528434302@qq.com	China	282	58
Wuhan Jieyou Shun Chemical Technology Co., Ltd.	18062118104; 18062118104	3932636749@qq.com	China	294	58
Shandong Jiaming Chemical Co., Ltd.	18615658326 18615658326	18615658326@163.com	China	61	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
ShangHai DEMO Chemical Co.,Ltd	400-021-7337 2355568890	sales@demochem.com	China	2569	57
Energy Chemical	400-0056266 18918157536;	sales8178@energy-chemical.com	China	45000	61
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Beckmann-Kenko GmbH	+49 4241 9308 88	info@beckmann-kenko.com	Germany	478	62

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