데스모스테롤-d6

데스모스테롤-d6 C화학적 특성, 용도, 생산

개요

24-dehydro Cholesterol-d₆ is intended for use as an internal standard for the quantification of 24-dehydro cholesterol by GC- or LC-MS. 24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions.

용도

A labelled metabolite of Cholesterol (C432501).

데스모스테롤-d6 준비 용품 및 원자재

원자재

준비 용품

데스모스테롤-d6 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8073	58
Codow Chemical Co.,Ltd.	18620099427	amy@howeipharm.com	China	17698	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9708	58
Chengdu Dianchun Technology Co., Ltd	400-1166-196 18502815961	cdhxsj@163.com	China	14623	60
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	56057	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58