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Desmosterol-d6

CAS No.
1246298-67-8
Chemical Name:
Desmosterol-d6
Synonyms
Desmosterol-d6;[2H6]-Desmosterol;24-dehydro Cholesterol-d6;cholesta-5,24-dien-3-ol-d6;cholesta-5,24-dien-3β-ol-d6;Desmosterol-26,26,26,27,27,27-d6;CHOLESTA-5,24-DIEN-3-OL-D6;DESMOSTEROL-D6
CBNumber:
CB72512379
Molecular Formula:
C27H44O
Molecular Weight:
384.63766
MDL Number:
MFCD22416725
MOL File:
1246298-67-8.mol
Last updated:2023-05-18 11:31:17

Desmosterol-d6 Properties

Melting point 114-116°C
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly, Sonicated)
form Solid
color Off-White to Light Beige

Desmosterol-d6 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 26777 24-dehydro Cholesterol-d6 1246298-67-8 500μg $121 2024-03-01 Buy
Cayman Chemical 26777 24-dehydro Cholesterol-d6 1246298-67-8 1mg $230 2024-03-01 Buy
TRC D296862 Desmosterol-d6 1246298-67-8 1mg $245 2021-12-16 Buy
Product number Packaging Price Buy
26777 500μg $121 Buy
26777 1mg $230 Buy
D296862 1mg $245 Buy

Desmosterol-d6 Chemical Properties,Uses,Production

Description

24-dehydro Cholesterol-d6 is intended for use as an internal standard for the quantification of 24-dehydro cholesterol by GC- or LC-MS. 24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions.

Uses

A labelled metabolite of Cholesterol (C432501).

Desmosterol-d6 Preparation Products And Raw materials

Raw materials

Preparation Products

Desmosterol-d6 Suppliers

Global( 27)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8073 58
Codow Chemical Co.,Ltd. 18620099427 amy@howeipharm.com China 17698 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Chengdu Dianchun Technology Co., Ltd 400-1166-196 18502815961 cdhxsj@163.com China 14623 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 56070 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Desmosterol-d6 CHOLESTA-5,24-DIEN-3-OL-D6;DESMOSTEROL-D6 cholesta-5,24-dien-3-ol-d6 24-dehydro Cholesterol-d6 [2H6]-Desmosterol Desmosterol-26,26,26,27,27,27-d6 cholesta-5,24-dien-3β-ol-d6 1246298-67-8 C27H38D6O Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids Intermediates & Fine Chemicals Isotope Labelled Compounds Metabolites & Impurities Pharmaceuticals Steroids